RPS27

RPS27

Ribosomal protein S27 (metallopanstimulin 1), also known as RPS27, is a human gene.cite web | title = Entrez Gene: RPS27 ribosomal protein S27 (metallopanstimulin 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6232| accessdate = ]

PBB_Summary
section_title =
summary_text = Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.cite web | title = Entrez Gene: RPS27 ribosomal protein S27 (metallopanstimulin 1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6232| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11-12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=
*cite journal | author=Fernandez-Pol JA, Klos DJ, Hamilton PD |title=Metallopanstimulin gene product produced in a baculovirus expression system is a nuclear phosphoprotein that binds to DNA. |journal=Cell Growth Differ. |volume=5 |issue= 8 |pages= 811–25 |year= 1995 |pmid= 7986747 |doi=
*cite journal | author=Fernandez-Pol JA, Klos DJ, Hamilton PD |title=A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure. |journal=J. Biol. Chem. |volume=268 |issue= 28 |pages= 21198–204 |year= 1993 |pmid= 8407955 |doi=
*cite journal | author=Vladimirov SN, Ivanov AV, Karpova GG, "et al." |title=Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. |journal=Eur. J. Biochem. |volume=239 |issue= 1 |pages= 144–9 |year= 1996 |pmid= 8706699 |doi=
*cite journal | author=Tsui SK, Lee SM, Fung KP, "et al." |title=Primary structures and sequence analysis of human ribosomal proteins L39 and S27. |journal=Biochem. Mol. Biol. Int. |volume=40 |issue= 3 |pages= 611–6 |year= 1997 |pmid= 8908372 |doi=
*cite journal | author=Kenmochi N, Kawaguchi T, Rozen S, "et al." |title=A map of 75 human ribosomal protein genes. |journal=Genome Res. |volume=8 |issue= 5 |pages= 509–23 |year= 1998 |pmid= 9582194 |doi=
*cite journal | author=Yoshihama M, Uechi T, Asakawa S, "et al." |title=The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. |journal=Genome Res. |volume=12 |issue= 3 |pages= 379–90 |year= 2002 |pmid= 11875025 |doi= 10.1101/gr.214202
*cite journal | author=Atsuta Y, Aoki N, Sato K, "et al." |title=Identification of metallopanstimulin-1 as a member of a tumor associated antigen in patients with breast cancer. |journal=Cancer Lett. |volume=182 |issue= 1 |pages= 101–7 |year= 2002 |pmid= 12175529 |doi=
*cite journal | author=Martin-Lluesma S, Stucke VM, Nigg EA |title=Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. |journal=Science |volume=297 |issue= 5590 |pages= 2267–70 |year= 2002 |pmid= 12351790 |doi= 10.1126/science.1075596
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Liu ST, Chan GK, Hittle JC, "et al." |title=Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores. |journal=Mol. Biol. Cell |volume=14 |issue= 4 |pages= 1638–51 |year= 2003 |pmid= 12686615 |doi= 10.1091/mbc.02-05-0074
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Yu Y, Ji H, Doudna JA, Leary JA |title=Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. |journal=Protein Sci. |volume=14 |issue= 6 |pages= 1438–46 |year= 2005 |pmid= 15883184 |doi= 10.1110/ps.041293005
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Bhonde MR, Hanski ML, Budczies J, "et al." |title=DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis. |journal=J. Biol. Chem. |volume=281 |issue= 13 |pages= 8675–85 |year= 2006 |pmid= 16446370 |doi= 10.1074/jbc.M511333200
*cite journal | author=Wang YW, Qu Y, Li JF, "et al." |title=In vitro and in vivo evidence of metallopanstimulin-1 in gastric cancer progression and tumorigenicity. |journal=Clin. Cancer Res. |volume=12 |issue= 16 |pages= 4965–73 |year= 2006 |pmid= 16914586 |doi= 10.1158/1078-0432.CCR-05-2316
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026

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