FLOT2

Flotillin 2, also known as FLOT2, is a human gene.cite web | title = Entrez Gene: FLOT2 flotillin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2319| accessdate = ]

PBB_Summary
section_title =
summary_text = Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling.cite web | title = Entrez Gene: FLOT2 flotillin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2319| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Schroeder WT, Siciliano MJ, Stewart-Galetka SL, Duvic M |title=The human gene for an epidermal surface antigen (M17S1) is located at 17q11-12. |journal=Genomics |volume=11 |issue= 2 |pages= 481–2 |year= 1992 |pmid= 1769667 |doi=
*cite journal | author=Schroeder WT, Stewart-Galetka S, Mandavilli S, "et al." |title=Cloning and characterization of a novel epidermal cell surface antigen (ESA). |journal=J. Biol. Chem. |volume=269 |issue= 31 |pages= 19983–91 |year= 1994 |pmid= 8051082 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Volonte D, Galbiati F, Li S, "et al." |title=Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe. |journal=J. Biol. Chem. |volume=274 |issue= 18 |pages= 12702–9 |year= 1999 |pmid= 10212252 |doi=
*cite journal | author=Hazarika P, Dham N, Patel P, "et al." |title=Flotillin 2 is distinct from epidermal surface antigen (ESA) and is associated with filopodia formation. |journal=J. Cell. Biochem. |volume=75 |issue= 1 |pages= 147–59 |year= 1999 |pmid= 10462713 |doi=
*cite journal | author=Salzer U, Prohaska R |title=Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts. |journal=Blood |volume=97 |issue= 4 |pages= 1141–3 |year= 2001 |pmid= 11159550 |doi=
*cite journal | author=Solomon S, Masilamani M, Rajendran L, "et al." |title=The lipid raft microdomain-associated protein reggie-1/flotillin-2 is expressed in human B cells and localized at the plasma membrane and centrosome in PBMCs. |journal=Immunobiology |volume=205 |issue= 1 |pages= 108–19 |year= 2002 |pmid= 11999340 |doi=
*cite journal | author=Wistow G, Bernstein SL, Wyatt MK, "et al." |title=Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants. |journal=Mol. Vis. |volume=8 |issue= |pages= 205–20 |year= 2002 |pmid= 12107410 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Shin BK, Wang H, Yim AM, "et al." |title=Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function. |journal=J. Biol. Chem. |volume=278 |issue= 9 |pages= 7607–16 |year= 2003 |pmid= 12493773 |doi= 10.1074/jbc.M210455200
*cite journal | author=Lehner B, Semple JI, Brown SE, "et al." |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153–67 |year= 2004 |pmid= 14667819 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hazarika P, McCarty MF, Prieto VG, "et al." |title=Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1. |journal=Cancer Res. |volume=64 |issue= 20 |pages= 7361–9 |year= 2004 |pmid= 15492257 |doi= 10.1158/0008-5472.CAN-04-0823
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Bracho C, Dunia I, Romano M, "et al." |title=Caveolins and flotillin-2 are present in the blood stages of Plasmodium vivax. |journal=Parasitol. Res. |volume=99 |issue= 2 |pages= 153–9 |year= 2006 |pmid= 16521037 |doi= 10.1007/s00436-006-0139-6
*cite journal | author=Doherty SD, Prieto VG, George S, "et al." |title=High flotillin-2 expression is associated with lymph node metastasis and Breslow depth in melanoma. |journal=Melanoma Res. |volume=16 |issue= 5 |pages= 461–3 |year= 2007 |pmid= 17013097 |doi= 10.1097/01.cmr.0000222592.75858.20
*cite journal | author=Jiang M, Ding Y, Su Y, "et al." |title=Arginase-flotillin interaction brings arginase to red blood cell membrane. |journal=FEBS Lett. |volume=580 |issue= 28-29 |pages= 6561–4 |year= 2007 |pmid= 17113085 |doi= 10.1016/j.febslet.2006.11.003
*cite journal | author=Sugawara Y, Nishii H, Takahashi T, "et al." |title=The lipid raft proteins flotillins/reggies interact with Galphaq and are involved in Gq-mediated p38 mitogen-activated protein kinase activation through tyrosine kinase. |journal=Cell. Signal. |volume=19 |issue= 6 |pages= 1301–8 |year= 2007 |pmid= 17307333 |doi= 10.1016/j.cellsig.2007.01.012
*cite journal | author=Langhorst MF, Solis GP, Hannbeck S, "et al." |title=Linking membrane microdomains to the cytoskeleton: regulation of the lateral mobility of reggie-1/flotillin-2 by interaction with actin. |journal=FEBS Lett. |volume=581 |issue= 24 |pages= 4697–703 |year= 2007 |pmid= 17854803 |doi= 10.1016/j.febslet.2007.08.074

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