PFDN1

Prefoldin subunit 1, also known as PFDN1, is a human gene.

PBB_Summary
section_title =
summary_text = This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.cite web | title = Entrez Gene: PFDN1 prefoldin subunit 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5201| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hartl FU, Hayer-Hartl M |title=Molecular chaperones in the cytosol: from nascent chain to folded protein. |journal=Science |volume=295 |issue= 5561 |pages= 1852–8 |year= 2002 |pmid= 11884745 |doi= 10.1126/science.1068408
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8
*cite journal | author=Iijima M, Kano Y, Nohno T, Namba M |title=Cloning of cDNA with possible transcription factor activity at the G1-S phase transition in human fibroblast cell lines. |journal=Acta Med. Okayama |volume=50 |issue= 2 |pages= 73–7 |year= 1996 |pmid= 8744932 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3
*cite journal | author=Vainberg IE, Lewis SA, Rommelaere H, "et al." |title=Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. |journal=Cell |volume=93 |issue= 5 |pages= 863–73 |year= 1998 |pmid= 9630229 |doi=10.1016/S0092-8674(00)81446-4
*cite journal | author=Horrigan SK, Bartoloni L, Speer MC, "et al." |title=A radiation hybrid breakpoint map of the acute myeloid leukemia (AML) and limb-girdle muscular dystrophy 1A (LGMD1A) regions of chromosome 5q31 localizing 122 expressed sequences. |journal=Genomics |volume=57 |issue= 1 |pages= 24–35 |year= 1999 |pmid= 10191080 |doi= 10.1006/geno.1999.5765
*cite journal | author=Hansen WJ, Cowan NJ, Welch WJ |title=Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins. |journal=J. Cell Biol. |volume=145 |issue= 2 |pages= 265–77 |year= 1999 |pmid= 10209023 |doi=10.1083/jcb.145.2.265
*cite journal | author=Cowan NJ, Lewis SA |title=A chaperone with a hydrophilic surface. |journal=Nat. Struct. Biol. |volume=6 |issue= 11 |pages= 990–1 |year= 2002 |pmid= 10542082 |doi= 10.1038/14870
*cite journal | author=Munnia A, Schütz N, Romeike BF, "et al." |title=Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor. |journal=Oncogene |volume=20 |issue= 35 |pages= 4853–63 |year= 2001 |pmid= 11521196 |doi= 10.1038/sj.onc.1204650
*cite journal | author=Rommelaere H, De Neve M, Neirynck K, "et al." |title=Prefoldin recognition motifs in the nonhomologous proteins of the actin and tubulin families. |journal=J. Biol. Chem. |volume=276 |issue= 44 |pages= 41023–8 |year= 2001 |pmid= 11535601 |doi= 10.1074/jbc.M106591200
*cite journal | author=Martín-Benito J, Boskovic J, Gómez-Puertas P, "et al." |title=Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT. |journal=Embo J. |volume=21 |issue= 23 |pages= 6377–86 |year= 2003 |pmid= 12456645 |doi=10.1093/emboj/cdf640
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bruneel A, Labas V, Mailloux A, "et al." |title=Proteomic study of human umbilical vein endothelial cells in culture. |journal=Proteomics |volume=3 |issue= 5 |pages= 714–23 |year= 2004 |pmid= 12748950 |doi= 10.1002/pmic.200300409
*cite journal | author=Gstaiger M, Luke B, Hess D, "et al." |title=Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. |journal=Science |volume=302 |issue= 5648 |pages= 1208–12 |year= 2003 |pmid= 14615539 |doi= 10.1126/science.1088401
*cite journal | author=Simons CT, Staes A, Rommelaere H, "et al." |title=Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding. |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4196–203 |year= 2004 |pmid= 14634002 |doi= 10.1074/jbc.M306053200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

PBB_Controls
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