PIP5K3

Phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III, also known as PIP5K3, is a human gene.cite web | title = Entrez Gene: PIP5K3 phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=200576| accessdate = ]

PBB_Summary
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summary_text = PIP5K3 belongs to a large family of lipid kinases that alter the phosphorylation status of intracellular phosphatidylinositol. Signaling by phosphorylated species of phosphatidylinositol regulates diverse cellular processes, including membrane trafficking and cytoskeletal reorganization (Shisheva et al., 1999). [supplied by OMIM] cite web | title = Entrez Gene: PIP5K3 phosphatidylinositol-3-phosphate/phosphatidylinositol 5-kinase, type III| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=200576| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Carpenter CL |title=Btk-dependent regulation of phosphoinositide synthesis. |journal=Biochem. Soc. Trans. |volume=32 |issue= Pt 2 |pages= 326–9 |year= 2004 |pmid= 15046600 |doi= 10.1042/
*cite journal | author=Shisheva A, Sbrissa D, Ikonomov O |title=Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells. |journal=Mol. Cell. Biol. |volume=19 |issue= 1 |pages= 623–34 |year= 1999 |pmid= 9858586 |doi=
*cite journal | author=Nagase T, Ishikawa K, Suyama M, "et al." |title=Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 1 |pages= 63–70 |year= 1999 |pmid= 10231032 |doi=
*cite journal | author=Sbrissa D, Ikonomov OC, Shisheva A |title=Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization. |journal=J. Biol. Chem. |volume=277 |issue= 8 |pages= 6073–9 |year= 2002 |pmid= 11706043 |doi= 10.1074/jbc.M110194200
*cite journal | author=Sbrissa D, Ikonomov OC, Deeb R, Shisheva A |title=Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells. |journal=J. Biol. Chem. |volume=277 |issue= 49 |pages= 47276–84 |year= 2003 |pmid= 12270933 |doi= 10.1074/jbc.M207576200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Jiao X, Munier FL, Schorderet DF, "et al." |title=Genetic linkage of Francois-Neetens fleck (mouchetée) corneal dystrophy to chromosome 2q35. |journal=Hum. Genet. |volume=112 |issue= 5-6 |pages= 593–9 |year= 2003 |pmid= 12607114 |doi= 10.1007/s00439-002-0905-1
*cite journal | author=Ikonomov OC, Sbrissa D, Mlak K, "et al." |title=Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 50863–71 |year= 2004 |pmid= 14530284 |doi= 10.1074/jbc.M307260200
*cite journal | author=Ikonomov OC, Sbrissa D, Foti M, "et al." |title=PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesis. |journal=Mol. Biol. Cell |volume=14 |issue= 11 |pages= 4581–91 |year= 2004 |pmid= 14551253 |doi= 10.1091/mbc.E03-04-0222
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Brill LM, Salomon AR, Ficarro SB, "et al." |title=Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. |journal=Anal. Chem. |volume=76 |issue= 10 |pages= 2763–72 |year= 2004 |pmid= 15144186 |doi= 10.1021/ac035352d
*cite journal | author=Yang SA, Carpenter CL, Abrams CS |title=Rho and Rho-kinase mediate thrombin-induced phosphatidylinositol 4-phosphate 5-kinase trafficking in platelets. |journal=J. Biol. Chem. |volume=279 |issue= 40 |pages= 42331–6 |year= 2004 |pmid= 15277528 |doi= 10.1074/jbc.M404335200
*cite journal | author=Sbrissa D, Ikonomov OC, Strakova J, "et al." |title=A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity. |journal=Mol. Cell. Biol. |volume=24 |issue= 23 |pages= 10437–47 |year= 2005 |pmid= 15542851 |doi= 10.1128/MCB.24.23.10437-10447.2004
*cite journal | author=Rush J, Moritz A, Lee KA, "et al." |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046
*cite journal | author=Li S, Tiab L, Jiao X, "et al." |title=Mutations in PIP5K3 are associated with François-Neetens mouchetée fleck corneal dystrophy. |journal=Am. J. Hum. Genet. |volume=77 |issue= 1 |pages= 54–63 |year= 2005 |pmid= 15902656 |doi= 10.1086/431346
*cite journal | author=Cabezas A, Pattni K, Stenmark H |title=Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1. |journal=Gene |volume=371 |issue= 1 |pages= 34–41 |year= 2006 |pmid= 16448788 |doi= 10.1016/j.gene.2005.11.009
*cite journal | author=Rutherford AC, Traer C, Wassmer T, "et al." |title=The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. |journal=J. Cell. Sci. |volume=119 |issue= Pt 19 |pages= 3944–57 |year= 2007 |pmid= 16954148 |doi= 10.1242/jcs.03153
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Araki N, Hamasaki M, Egami Y, Hatae T |title=Effect of 3-methyladenine on the fusion process of macropinosomes in EGF-stimulated A431 cells. |journal=Cell Struct. Funct. |volume=31 |issue= 2 |pages= 145–57 |year= 2007 |pmid= 17146146 |doi=

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