FUSIP1

FUS interacting protein (serine/arginine-rich) 1, also known as FUSIP1, is a human gene.cite web | title = Entrez Gene: FUSIP1 FUS interacting protein (serine/arginine-rich) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10772| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.cite web | title = Entrez Gene: FUSIP1 FUS interacting protein (serine/arginine-rich) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10772| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Yang L, Embree LJ, Tsai S, Hickstein DD |title=Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing. |journal=J. Biol. Chem. |volume=273 |issue= 43 |pages= 27761–4 |year= 1998 |pmid= 9774382 |doi=
*cite journal | author=Yang L, Embree LJ, Hickstein DD |title=TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins. |journal=Mol. Cell. Biol. |volume=20 |issue= 10 |pages= 3345–54 |year= 2000 |pmid= 10779324 |doi=
*cite journal | author=Cowper AE, Cáceres JF, Mayeda A, Screaton GR |title=Serine-arginine (SR) protein-like factors that antagonize authentic SR proteins and regulate alternative splicing. |journal=J. Biol. Chem. |volume=276 |issue= 52 |pages= 48908–14 |year= 2002 |pmid= 11684676 |doi= 10.1074/jbc.M103967200
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Clinton JM, Chansky HA, Odell DD, "et al." |title=Characterization and expression of the human gene encoding two translocation liposarcoma protein-associated serine-arginine (TASR) proteins. |journal=Gene |volume=284 |issue= 1-2 |pages= 141–7 |year= 2002 |pmid= 11891055 |doi=
*cite journal | author=Shin C, Manley JL |title=The SR protein SRp38 represses splicing in M phase cells. |journal=Cell |volume=111 |issue= 3 |pages= 407–17 |year= 2002 |pmid= 12419250 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Li J, Hawkins IC, Harvey CD, "et al." |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437–47 |year= 2003 |pmid= 14559993 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Shin C, Feng Y, Manley JL |title=Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. |journal=Nature |volume=427 |issue= 6974 |pages= 553–8 |year= 2004 |pmid= 14765198 |doi= 10.1038/nature02288
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Benzinger A, Muster N, Koch HB, "et al." |title=Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. |journal=Mol. Cell Proteomics |volume=4 |issue= 6 |pages= 785–95 |year= 2005 |pmid= 15778465 |doi= 10.1074/mcp.M500021-MCP200
*cite journal | author=Shin C, Kleiman FE, Manley JL |title=Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins. |journal=Mol. Cell. Biol. |volume=25 |issue= 18 |pages= 8334–43 |year= 2005 |pmid= 16135820 |doi= 10.1128/MCB.25.18.8334-8343.2005
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209

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