VPS35

Vacuolar protein sorting 35 homolog (S. cerevisiae), also known as VPS35, is a human gene.cite web | title = Entrez Gene: VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55737| accessdate = ]

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.cite web | title = Entrez Gene: VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55737| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
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