RASD1

RASD1

RAS, dexamethasone-induced 1, also known as RASD1, is a human gene.cite web | title = Entrez Gene: RASD1 RAS, dexamethasone-induced 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51655| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.cite web | title = Entrez Gene: RASD1 RAS, dexamethasone-induced 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51655| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kemppainen RJ, Behrend EN |title=Dexamethasone rapidly induces a novel ras superfamily member-related gene in AtT-20 cells. |journal=J. Biol. Chem. |volume=273 |issue= 6 |pages= 3129–31 |year= 1998 |pmid= 9452419 |doi=
*cite journal | author=Cismowski MJ, Takesono A, Ma C, "et al." |title=Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling. |journal=Nat. Biotechnol. |volume=17 |issue= 9 |pages= 878–83 |year= 1999 |pmid= 10471929 |doi= 10.1038/12867
*cite journal | author=Tu Y, Wu C |title=Cloning, expression and characterization of a novel human Ras-related protein that is regulated by glucocorticoid hormone. |journal=Biochim. Biophys. Acta |volume=1489 |issue= 2-3 |pages= 452–6 |year= 2000 |pmid= 10673050 |doi=
*cite journal | author=Cismowski MJ, Ma C, Ribas C, "et al." |title=Activation of heterotrimeric G-protein signaling by a ras-related protein. Implications for signal integration. |journal=J. Biol. Chem. |volume=275 |issue= 31 |pages= 23421–4 |year= 2000 |pmid= 10840027 |doi= 10.1074/jbc.C000322200
*cite journal | author=St Croix B, Rago C, Velculescu V, "et al." |title=Genes expressed in human tumor endothelium. |journal=Science |volume=289 |issue= 5482 |pages= 1197–202 |year= 2000 |pmid= 10947988 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Fang M, Jaffrey SR, Sawa A, "et al." |title=Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. |journal=Neuron |volume=28 |issue= 1 |pages= 183–93 |year= 2000 |pmid= 11086993 |doi=
*cite journal | author=Ognjanovic S, Bao S, Yamamoto SY, "et al." |title=Genomic organization of the gene coding for human pre-B-cell colony enhancing factor and expression in human fetal membranes. |journal=J. Mol. Endocrinol. |volume=26 |issue= 2 |pages= 107–17 |year= 2001 |pmid= 11241162 |doi=
*cite journal | author=Takesono A, Nowak MW, Cismowski M, "et al." |title=Activator of G-protein signaling 1 blocks GIRK channel activation by a G-protein-coupled receptor: apparent disruption of receptor signaling complexes. |journal=J. Biol. Chem. |volume=277 |issue= 16 |pages= 13827–30 |year= 2002 |pmid= 11842095 |doi= 10.1074/jbc.M201064200
*cite journal | author=Bi W, Yan J, Stankiewicz P, "et al." |title=Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse. |journal=Genome Res. |volume=12 |issue= 5 |pages= 713–28 |year= 2002 |pmid= 11997338 |doi= 10.1101/gr.73702
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Jaffrey SR, Fang M, Snyder SH |title=Nitrosopeptide mapping: a novel methodology reveals s-nitrosylation of dexras1 on a single cysteine residue. |journal=Chem. Biol. |volume=9 |issue= 12 |pages= 1329–35 |year= 2003 |pmid= 12498886 |doi=
*cite journal | author=Kemppainen RJ, Cox E, Behrend EN, "et al." |title=Identification of a glucocorticoid response element in the 3'-flanking region of the human Dexras1 gene. |journal=Biochim. Biophys. Acta |volume=1627 |issue= 2-3 |pages= 85–9 |year= 2003 |pmid= 12818426 |doi=
*cite journal | author=Vaidyanathan G, Cismowski MJ, Wang G, "et al." |title=The Ras-related protein AGS1/RASD1 suppresses cell growth. |journal=Oncogene |volume=23 |issue= 34 |pages= 5858–63 |year= 2004 |pmid= 15184869 |doi= 10.1038/sj.onc.1207774
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Hiskens R, Vatish M, Hill C, "et al." |title=Specific in vivo binding of activator of G protein signalling 1 to the Gbeta1 subunit. |journal=Biochem. Biophys. Res. Commun. |volume=337 |issue= 4 |pages= 1038–46 |year= 2005 |pmid= 16225846 |doi= 10.1016/j.bbrc.2005.09.149
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Nguyen CH, Watts VJ |title=Dexamethasone-induced Ras protein 1 negatively regulates protein kinase C delta: implications for adenylyl cyclase 2 signaling. |journal=Mol. Pharmacol. |volume=69 |issue= 5 |pages= 1763–71 |year= 2006 |pmid= 16489124 |doi= 10.1124/mol.105.019133

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  • Ras (protein) — Pfam box Symbol = Ras Name = width =250 caption = Triphosphate Structure of H Ras p21 GNBP in complex with GppNHp and Mg2+ (PDB Code 5p21). Important sequence elements are highlighted. Pfam= PF00071 InterPro= IPR013753 SMART= PROSITE = PDOC00859… …   Wikipedia

  • NOS1AP — Nitric oxide synthase 1 (neuronal) adaptor protein Identifiers Symbols NOS1AP; 6330408P19Rik; CAPON; MGC138500 External IDs …   Wikipedia

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