CHAF1B

Chromatin assembly factor 1, subunit B (p60), also known as CHAF1B, is a human gene.cite web | title = Entrez Gene: CHAF1B chromatin assembly factor 1, subunit B (p60)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8208| accessdate = ]

PBB_Summary
section_title =
summary_text = Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.cite web | title = Entrez Gene: CHAF1B chromatin assembly factor 1, subunit B (p60)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8208| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ridgway P, Almouzni G |title=CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair. |journal=J. Cell. Sci. |volume=113 ( Pt 15) |issue= |pages= 2647–58 |year= 2000 |pmid= 10893180 |doi=
*cite journal | author=Kaufman PD, Kobayashi R, Kessler N, Stillman B |title=The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. |journal=Cell |volume=81 |issue= 7 |pages= 1105–14 |year= 1995 |pmid= 7600578 |doi=
*cite journal | author=Blouin JL, Duriaux-Sail G, Chen H, "et al." |title=Mapping of the gene for the p60 subunit of the human chromatin assembly factor (CAF1A) to the Down syndrome region of chromosome 21. |journal=Genomics |volume=33 |issue= 2 |pages= 309–12 |year= 1997 |pmid= 8660983 |doi= 10.1006/geno.1996.0199
*cite journal | author=Katsanis N, Fisher EM |title=The gene encoding the p60 subunit of chromatin assembly factor I (CAF1P60) maps to human chromosome 21q22.2, a region associated with some of the major features of Down syndrome. |journal=Hum. Genet. |volume=98 |issue= 4 |pages= 497–9 |year= 1996 |pmid= 8792829 |doi=
*cite journal | author=Verreault A, Kaufman PD, Kobayashi R, Stillman B |title=Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. |journal=Cell |volume=87 |issue= 1 |pages= 95–104 |year= 1996 |pmid= 8858152 |doi=
*cite journal | author=Matsumoto-Taniura N, Pirollet F, Monroe R, "et al." |title=Identification of novel M phase phosphoproteins by expression cloning. |journal=Mol. Biol. Cell |volume=7 |issue= 9 |pages= 1455–69 |year= 1997 |pmid= 8885239 |doi=
*cite journal | author=Marheineke K, Krude T |title=Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle. |journal=J. Biol. Chem. |volume=273 |issue= 24 |pages= 15279–86 |year= 1998 |pmid= 9614144 |doi=
*cite journal | author=Martini E, Roche DM, Marheineke K, "et al." |title=Recruitment of phosphorylated chromatin assembly factor 1 to chromatin after UV irradiation of human cells. |journal=J. Cell Biol. |volume=143 |issue= 3 |pages= 563–75 |year= 1998 |pmid= 9813080 |doi=
*cite journal | author=Hattori M, Fujiyama A, Taylor TD, "et al." |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311–9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518
*cite journal | author=Keller C, Krude T |title=Requirement of Cyclin/Cdk2 and protein phosphatase 1 activity for chromatin assembly factor 1-dependent chromatin assembly during DNA synthesis. |journal=J. Biol. Chem. |volume=275 |issue= 45 |pages= 35512–21 |year= 2001 |pmid= 10938080 |doi= 10.1074/jbc.M003073200
*cite journal | author=Mello JA, Silljé HH, Roche DM, "et al." |title=Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. |journal=EMBO Rep. |volume=3 |issue= 4 |pages= 329–34 |year= 2002 |pmid= 11897662 |doi= 10.1093/embo-reports/kvf068
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Morel AP, Sentis S, Bianchin C, "et al." |title=BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms. |journal=J. Cell. Sci. |volume=116 |issue= Pt 14 |pages= 2929–36 |year= 2004 |pmid= 12771185 |doi= 10.1242/jcs.00480
*cite journal | author=Nabatiyan A, Krude T |title=Silencing of chromatin assembly factor 1 in human cells leads to cell death and loss of chromatin assembly during DNA synthesis. |journal=Mol. Cell. Biol. |volume=24 |issue= 7 |pages= 2853–62 |year= 2004 |pmid= 15024074 |doi=
*cite journal | author=Shim KS, Bergelson JM, Furuse M, "et al." |title=Reduction of chromatin assembly factor 1 p60 and C21orf2 protein, encoded on chromosome 21, in Down syndrome brain. |journal=J. Neural Transm. Suppl. |volume= |issue= 67 |pages= 117–28 |year= 2004 |pmid= 15068244 |doi=
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Lin KT, Lu RM, Tarn WY |title=The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo. |journal=Mol. Cell. Biol. |volume=24 |issue= 20 |pages= 9176–85 |year= 2004 |pmid= 15456888 |doi= 10.1128/MCB.24.20.9176-9185.2004
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Groth A, Ray-Gallet D, Quivy JP, "et al." |title=Human Asf1 regulates the flow of S phase histones during replicational stress. |journal=Mol. Cell |volume=17 |issue= 2 |pages= 301–11 |year= 2005 |pmid= 15664198 |doi= 10.1016/j.molcel.2004.12.018

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