MAPRE2

Microtubule-associated protein, RP/EB family, member 2, also known as MAPRE2, is a human gene.cite web | title = Entrez Gene: MAPRE2 microtubule-associated protein, RP/EB family, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10982| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.cite web | title = Entrez Gene: MAPRE2 microtubule-associated protein, RP/EB family, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10982| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Tirnauer JS, Bierer BE |title=EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability. |journal=J. Cell Biol. |volume=149 |issue= 4 |pages= 761–6 |year= 2000 |pmid= 10811817 |doi=
*cite journal | author=Su LK, Burrell M, Hill DE, "et al." |title=APC binds to the novel protein EB1. |journal=Cancer Res. |volume=55 |issue= 14 |pages= 2972–7 |year= 1995 |pmid= 7606712 |doi=
*cite journal | author=Renner C, Pfitzenmeier JP, Gerlach K, "et al." |title=RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells. |journal=J. Immunol. |volume=159 |issue= 3 |pages= 1276–83 |year= 1997 |pmid= 9233623 |doi=
*cite journal | author=Berrueta L, Kraeft SK, Tirnauer JS, "et al." |title=The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 18 |pages= 10596–601 |year= 1998 |pmid= 9724749 |doi=
*cite journal | author=Morrison EE, Wardleworth BN, Askham JM, "et al." |title=EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle. |journal=Oncogene |volume=17 |issue= 26 |pages= 3471–7 |year= 1999 |pmid= 10030671 |doi= 10.1038/sj.onc.1202247
*cite journal | author=Juwana JP, Henderikx P, Mischo A, "et al." |title=EB/RP gene family encodes tubulin binding proteins. |journal=Int. J. Cancer |volume=81 |issue= 2 |pages= 275–84 |year= 1999 |pmid= 10188731 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Nakamura M, Zhou XZ, Lu KP |title=Critical role for the EB1 and APC interaction in the regulation of microtubule polymerization. |journal=Curr. Biol. |volume=11 |issue= 13 |pages= 1062–7 |year= 2001 |pmid= 11470413 |doi=
*cite journal | author=Askham JM, Vaughan KT, Goodson HV, Morrison EE |title=Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome. |journal=Mol. Biol. Cell |volume=13 |issue= 10 |pages= 3627–45 |year= 2003 |pmid= 12388762 |doi= 10.1091/mbc.E02-01-0061
*cite journal | author=Tirnauer JS, Canman JC, Salmon ED, Mitchison TJ |title=EB1 targets to kinetochores with attached, polymerizing microtubules. |journal=Mol. Biol. Cell |volume=13 |issue= 12 |pages= 4308–16 |year= 2003 |pmid= 12475954 |doi= 10.1091/mbc.E02-04-0236
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bu W, Su LK |title=Characterization of functional domains of human EB1 family proteins. |journal=J. Biol. Chem. |volume=278 |issue= 50 |pages= 49721–31 |year= 2004 |pmid= 14514668 |doi= 10.1074/jbc.M306194200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Rush J, Moritz A, Lee KA, "et al." |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046
*cite journal | author=Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, "et al." |title=CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. |journal=J. Cell Biol. |volume=168 |issue= 1 |pages= 141–53 |year= 2005 |pmid= 15631994 |doi= 10.1083/jcb.200405094
*cite journal | author=Xu H, Hebert MD |title=A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin. |journal=BMC Cell Biol. |volume=6 |issue= 1 |pages= 23 |year= 2006 |pmid= 15862129 |doi= 10.1186/1471-2121-6-23
*cite journal | author=Wang Y, Zhou X, Zhu H, "et al." |title=Overexpression of EB1 in human esophageal squamous cell carcinoma (ESCC) may promote cellular growth by activating beta-catenin/TCF pathway. |journal=Oncogene |volume=24 |issue= 44 |pages= 6637–45 |year= 2005 |pmid= 16007168 |doi= 10.1038/sj.onc.1208819

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