EEF1A2

Eukaryotic translation elongation factor 1 alpha 2, also known as EEF1A2, is a human gene.cite web | title = Entrez Gene: EEF1A2 eukaryotic translation elongation factor 1 alpha 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1917| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer.cite web | title = Entrez Gene: EEF1A2 eukaryotic translation elongation factor 1 alpha 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1917| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lee JM |title=The role of protein elongation factor eEF1A2 in ovarian cancer. |journal=Reprod. Biol. Endocrinol. |volume=1 |issue= |pages= 69 |year= 2004 |pmid= 14588074 |doi= 10.1186/1477-7827-1-69
*cite journal | author=Beh KJ |title=Immunoglobulin class specificity of non-agglutinating antibody produced in cattle following Brucella abortus 45/20 vaccination. |journal=Aust. Vet. J. |volume=51 |issue= 10 |pages= 481–3 |year= 1976 |pmid= 812466 |doi=
*cite journal | author=Lee S, Ann DK, Wang E |title=Cloning of human and mouse brain cDNAs coding for S1, the second member of the mammalian elongation factor-1 alpha gene family: analysis of a possible evolutionary pathway. |journal=Biochem. Biophys. Res. Commun. |volume=203 |issue= 3 |pages= 1371–7 |year= 1994 |pmid= 7945283 |doi=
*cite journal | author=Knudsen SM, Frydenberg J, Clark BF, Leffers H |title=Tissue-dependent variation in the expression of elongation factor-1 alpha isoforms: isolation and characterisation of a cDNA encoding a novel variant of human elongation-factor 1 alpha. |journal=Eur. J. Biochem. |volume=215 |issue= 3 |pages= 549–54 |year= 1993 |pmid= 8354261 |doi=
*cite journal | author=Wu-Baer F, Lane WS, Gaynor RB |title=Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA. |journal=J. Biol. Chem. |volume=271 |issue= 8 |pages= 4201–8 |year= 1996 |pmid= 8626763 |doi=
*cite journal | author=Lund A, Knudsen SM, Vissing H, "et al." |title=Assignment of human elongation factor 1alpha genes: EEF1A maps to chromosome 6q14 and EEF1A2 to 20q13.3. |journal=Genomics |volume=36 |issue= 2 |pages= 359–61 |year= 1997 |pmid= 8812466 |doi= 10.1006/geno.1996.0475
*cite journal | author=Bischoff C, Kahns S, Lund A, "et al." |title=The human elongation factor 1 A-2 gene (EEF1A2): complete sequence and characterization of gene structure and promoter activity. |journal=Genomics |volume=68 |issue= 1 |pages= 63–70 |year= 2001 |pmid= 10950927 |doi= 10.1006/geno.2000.6271
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=McClatchy DB, Knudsen CR, Clark BF, "et al." |title=Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2. |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 29268–74 |year= 2002 |pmid= 12048193 |doi= 10.1074/jbc.M203081200
*cite journal | author=Anand N, Murthy S, Amann G, "et al." |title=Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer. |journal=Nat. Genet. |volume=31 |issue= 3 |pages= 301–5 |year= 2002 |pmid= 12053177 |doi= 10.1038/ng904
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Bouwmeester T, Bauch A, Ruffner H, "et al." |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rush J, Moritz A, Lee KA, "et al." |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207
*cite journal | author=Byun HM, Suh D, Jeong Y, "et al." |title=Plasmid vectors harboring cellular promoters can induce prolonged gene expression in hematopoietic and mesenchymal progenitor cells. |journal=Biochem. Biophys. Res. Commun. |volume=332 |issue= 2 |pages= 518–23 |year= 2005 |pmid= 15893736 |doi= 10.1016/j.bbrc.2005.04.155
*cite journal | author=Ahmed M, Forsberg J, Bergsten P |title=Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry. |journal=J. Proteome Res. |volume=4 |issue= 3 |pages= 931–40 |year= 2005 |pmid= 15952740 |doi= 10.1021/pr050024a
*cite journal | author=Tomlinson VA, Newbery HJ, Wray NR, "et al." |title=Translation elongation factor eEF1A2 is a potential oncoprotein that is overexpressed in two-thirds of breast tumours. |journal=BMC Cancer |volume=5 |issue= |pages= 113 |year= 2006 |pmid= 16156888 |doi= 10.1186/1471-2407-5-113
*cite journal | author=Li R, Wang H, Bekele BN, "et al." |title=Identification of putative oncogenes in lung adenocarcinoma by a comprehensive functional genomic approach. |journal=Oncogene |volume=25 |issue= 18 |pages= 2628–35 |year= 2006 |pmid= 16369491 |doi= 10.1038/sj.onc.1209289

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes