ARPC1B

Actin related protein 2/3 complex, subunit 1B, 41kDa, also known as ARPC1B, is a human gene.cite web | title = Entrez Gene: ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10095| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.cite web | title = Entrez Gene: ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10095| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
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*cite journal | author=Welch MD, Iwamatsu A, Mitchison TJ |title=Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. |journal=Nature |volume=385 |issue= 6613 |pages= 265–9 |year= 1997 |pmid= 9000076 |doi= 10.1038/385265a0
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Rassenti LZ, Kipps TJ |title=Lack of allelic exclusion in B cell chronic lymphocytic leukemia. |journal=J. Exp. Med. |volume=185 |issue= 8 |pages= 1435–45 |year= 1997 |pmid= 9126924 |doi=
*cite journal | author=Welch MD, DePace AH, Verma S, "et al." |title=The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. |journal=J. Cell Biol. |volume=138 |issue= 2 |pages= 375–84 |year= 1997 |pmid= 9230079 |doi=
*cite journal | author=Machesky LM, Reeves E, Wientjes F, "et al." |title=Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins. |journal=Biochem. J. |volume=328 ( Pt 1) |issue= |pages= 105–12 |year= 1998 |pmid= 9359840 |doi=
*cite journal | author=Zhao X, Yang Z, Qian M, Zhu X |title=Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 2 |pages= 513–7 |year= 2001 |pmid= 11162547 |doi= 10.1006/bbrc.2000.4151
*cite journal | author=Volkmann N, Amann KJ, Stoilova-McPhie S, "et al." |title=Structure of Arp2/3 complex in its activated state and in actin filament branch junctions. |journal=Science |volume=293 |issue= 5539 |pages= 2456–9 |year= 2001 |pmid= 11533442 |doi= 10.1126/science.1063025
*cite journal | author=Robinson RC, Turbedsky K, Kaiser DA, "et al." |title=Crystal structure of Arp2/3 complex. |journal=Science |volume=294 |issue= 5547 |pages= 1679–84 |year= 2001 |pmid= 11721045 |doi= 10.1126/science.1066333
*cite journal | author=Gournier H, Goley ED, Niederstrasser H, "et al." |title=Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity. |journal=Mol. Cell |volume=8 |issue= 5 |pages= 1041–52 |year= 2002 |pmid= 11741539 |doi=
*cite journal | author=Hüfner K, Schell B, Aepfelbacher M, Linder S |title=The acidic regions of WASp and N-WASP can synergize with CDC42Hs and Rac1 to induce filopodia and lamellipodia. |journal=FEBS Lett. |volume=514 |issue= 2-3 |pages= 168–74 |year= 2002 |pmid= 11943145 |doi=
*cite journal | author=Kaneda A, Kaminishi M, Nakanishi Y, "et al." |title=Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers. |journal=Int. J. Cancer |volume=100 |issue= 1 |pages= 57–62 |year= 2002 |pmid= 12115587 |doi= 10.1002/ijc.10464
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Hillier LW, Fulton RS, Fulton LA, "et al." |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782
*cite journal | author=Vadlamudi RK, Li F, Barnes CJ, "et al." |title=p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate. |journal=EMBO Rep. |volume=5 |issue= 2 |pages= 154–60 |year= 2004 |pmid= 14749719 |doi= 10.1038/sj.embor.7400079
*cite journal | author=Kaneda A, Kaminishi M, Sugimura T, Ushijima T |title=Decreased expression of the seven ARP2/3 complex genes in human gastric cancers. |journal=Cancer Lett. |volume=212 |issue= 2 |pages= 203–10 |year= 2004 |pmid= 15279900 |doi= 10.1016/j.canlet.2004.03.020
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207

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