CTDP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1, also known as CTDP1, is a human gene.cite web | title = Entrez Gene: CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9150| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein which interacts with the carboxy-terminus of transcription initiation factor TFIIF, a transcription factor which regulates elongation as well as initiation by RNA polymerase II. The protein may also represent a component of an RNA polymerase II holoenzyme complex. Alternative splicing of this gene results in two transcript variants encoding 2 different isoforms.cite web | title = Entrez Gene: CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9150| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Scully R, Anderson SF, Chao DM, "et al." |title=BRCA1 is a component of the RNA polymerase II holoenzyme. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 11 |pages= 5605–10 |year= 1997 |pmid= 9159119 |doi=
*cite journal | author=Archambault J, Chambers RS, Kobor MS, "et al." |title=An essential component of a C-terminal domain phosphatase that interacts with transcription factor IIF in Saccharomyces cerevisiae. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 26 |pages= 14300–5 |year= 1998 |pmid= 9405607 |doi=
*cite journal | author=Archambault J, Pan G, Dahmus GK, "et al." |title=FCP1, the RAP74-interacting subunit of a human protein phosphatase that dephosphorylates the carboxyl-terminal domain of RNA polymerase IIO. |journal=J. Biol. Chem. |volume=273 |issue= 42 |pages= 27593–601 |year= 1998 |pmid= 9765293 |doi=
*cite journal | author=Marshall NF, Dahmus GK, Dahmus ME |title=Regulation of carboxyl-terminal domain phosphatase by HIV-1 tat protein. |journal=J. Biol. Chem. |volume=273 |issue= 48 |pages= 31726–30 |year= 1998 |pmid= 9822634 |doi=
*cite journal | author=Cho H, Kim TK, Mancebo H, "et al." |title=A protein phosphatase functions to recycle RNA polymerase II. |journal=Genes Dev. |volume=13 |issue= 12 |pages= 1540–52 |year= 1999 |pmid= 10385623 |doi=
*cite journal | author=Angelicheva D, Turnev I, Dye D, "et al." |title=Congenital cataracts facial dysmorphism neuropathy (CCFDN) syndrome: a novel developmental disorder in Gypsies maps to 18qter. |journal=Eur. J. Hum. Genet. |volume=7 |issue= 5 |pages= 560–6 |year= 1999 |pmid= 10439962 |doi= 10.1038/sj.ejhg.5200319
*cite journal | author=Marshall NF, Dahmus ME |title=C-terminal domain phosphatase sensitivity of RNA polymerase II in early elongation complexes on the HIV-1 and adenovirus 2 major late templates. |journal=J. Biol. Chem. |volume=275 |issue= 42 |pages= 32430–7 |year= 2000 |pmid= 10938286 |doi= 10.1074/jbc.M005898200
*cite journal | author=Licciardo P, Napolitano G, Majello B, Lania L |title=Inhibition of Tat transactivation by the RNA polymerase II CTD-phosphatase FCP1. |journal=AIDS |volume=15 |issue= 3 |pages= 301–7 |year= 2001 |pmid= 11273209 |doi=
*cite journal | author=Bharucha DC, Zhou M, Nekhai S, "et al." |title=A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat. |journal=Virology |volume=296 |issue= 1 |pages= 6–16 |year= 2002 |pmid= 12036313 |doi= 10.1006/viro.2002.1438
*cite journal | author=Washington K, Ammosova T, Beullens M, "et al." |title=Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40442–8 |year= 2002 |pmid= 12185079 |doi= 10.1074/jbc.M205687200
*cite journal | author=Mandal SS, Cho H, Kim S, "et al." |title=FCP1, a phosphatase specific for the heptapeptide repeat of the largest subunit of RNA polymerase II, stimulates transcription elongation. |journal=Mol. Cell. Biol. |volume=22 |issue= 21 |pages= 7543–52 |year= 2002 |pmid= 12370301 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Licciardo P, Amente S, Ruggiero L, "et al." |title=The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP. |journal=Nucleic Acids Res. |volume=31 |issue= 3 |pages= 999–1005 |year= 2003 |pmid= 12560496 |doi=
*cite journal | author=Nguyen BD, Chen HT, Kobor MS, "et al." |title=Solution structure of the carboxyl-terminal domain of RAP74 and NMR characterization of the FCP1-binding sites of RAP74 and human TFIIB. |journal=Biochemistry |volume=42 |issue= 6 |pages= 1460–9 |year= 2003 |pmid= 12578358 |doi= 10.1021/bi0265473
*cite journal | author=Friedl EM, Lane WS, Erdjument-Bromage H, "et al." |title=The C-terminal domain phosphatase and transcription elongation activities of FCP1 are regulated by phosphorylation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 5 |pages= 2328–33 |year= 2003 |pmid= 12591939 |doi= 10.1073/pnas.2628049100
*cite journal | author=Kamada K, Roeder RG, Burley SK |title=Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 5 |pages= 2296–9 |year= 2003 |pmid= 12591941 |doi= 10.1073/pnas.262798199
*cite journal | author=Nguyen BD, Abbott KL, Potempa K, "et al." |title=NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 10 |pages= 5688–93 |year= 2003 |pmid= 12732728 |doi= 10.1073/pnas.1031524100
*cite journal | author=Varon R, Gooding R, Steglich C, "et al." |title=Partial deficiency of the C-terminal-domain phosphatase of RNA polymerase II is associated with congenital cataracts facial dysmorphism neuropathy syndrome. |journal=Nat. Genet. |volume=35 |issue= 2 |pages= 185–9 |year= 2003 |pmid= 14517542 |doi= 10.1038/ng1243
*cite journal | author=Yu X, Chini CC, He M, "et al." |title=The BRCT domain is a phospho-protein binding domain. |journal=Science |volume=302 |issue= 5645 |pages= 639–42 |year= 2003 |pmid= 14576433 |doi= 10.1126/science.1088753
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101

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