HDAC7A

Histone deacetylase 7A, also known as HDAC7A, is a human gene.cite web | title = Entrez Gene: HDAC7A histone deacetylase 7A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51564| accessdate = ]

PBB_Summary
section_title =
summary_text = Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via transcriptional corepressor SMRT. Multiple alternatively spliced transcript variants encoding several isoforms have been found for this gene.cite web | title = Entrez Gene: HDAC7A histone deacetylase 7A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51564| accessdate = ]

ee also

* Histone deacetylase

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Marks PA, Richon VM, Rifkind RA |title=Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. |journal=J. Natl. Cancer Inst. |volume=92 |issue= 15 |pages= 1210–6 |year= 2000 |pmid= 10922406 |doi=
*cite journal | author=Verdin E, Dequiedt F, Kasler HG |title=Class II histone deacetylases: versatile regulators. |journal=Trends Genet. |volume=19 |issue= 5 |pages= 286–93 |year= 2003 |pmid= 12711221 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Kao HY, Downes M, Ordentlich P, Evans RM |title=Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. |journal=Genes Dev. |volume=14 |issue= 1 |pages= 55–66 |year= 2000 |pmid= 10640276 |doi=
*cite journal | author=Lee HJ, Chun M, Kandror KV |title=Tip60 and HDAC7 interact with the endothelin receptor a and may be involved in downstream signaling. |journal=J. Biol. Chem. |volume=276 |issue= 20 |pages= 16597–600 |year= 2001 |pmid= 11262386 |doi= 10.1074/jbc.C000909200
*cite journal | author=Fischle W, Dequiedt F, Fillion M, "et al." |title=Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo. |journal=J. Biol. Chem. |volume=276 |issue= 38 |pages= 35826–35 |year= 2001 |pmid= 11466315 |doi= 10.1074/jbc.M104935200
*cite journal | author=Lemercier C, Brocard MP, Puvion-Dutilleul F, "et al." |title=Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor. |journal=J. Biol. Chem. |volume=277 |issue= 24 |pages= 22045–52 |year= 2002 |pmid= 11929873 |doi= 10.1074/jbc.M201736200
*cite journal | author=Bryant H, Farrell PJ |title=Signal Transduction and Transcription Factor Modification during Reactivation of Epstein-Barr Virus from Latency. |journal=J. Virol. |volume=76 |issue= 20 |pages= 10290–8 |year= 2002 |pmid= 12239305 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Xiao H, Chung J, Kao HY, Yang YC |title=Tip60 is a co-repressor for STAT3. |journal=J. Biol. Chem. |volume=278 |issue= 13 |pages= 11197–204 |year= 2003 |pmid= 12551922 |doi= 10.1074/jbc.M210816200
*cite journal | author=Dequiedt F, Kasler H, Fischle W, "et al." |title=HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. |journal=Immunity |volume=18 |issue= 5 |pages= 687–98 |year= 2003 |pmid= 12753745 |doi=
*cite journal | author=Lee CH, Chawla A, Urbiztondo N, "et al." |title=Transcriptional repression of atherogenic inflammation: modulation by PPARdelta. |journal=Science |volume=302 |issue= 5644 |pages= 453–7 |year= 2003 |pmid= 12970571 |doi= 10.1126/science.1087344
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Li X, Song S, Liu Y, "et al." |title=Phosphorylation of the histone deacetylase 7 modulates its stability and association with 14-3-3 proteins. |journal=J. Biol. Chem. |volume=279 |issue= 33 |pages= 34201–8 |year= 2004 |pmid= 15166223 |doi= 10.1074/jbc.M405179200
*cite journal | author=Kato H, Tamamizu-Kato S, Shibasaki F |title=Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity. |journal=J. Biol. Chem. |volume=279 |issue= 40 |pages= 41966–74 |year= 2004 |pmid= 15280364 |doi= 10.1074/jbc.M406320200
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051

External links

*

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes