TACSTD2

Tumor-associated calcium signal transducer 2, also known as TACSTD2, is a human gene.cite web | title = Entrez Gene: TACSTD2 tumor-associated calcium signal transducer 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4070| accessdate = ]

PBB_Summary
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summary_text = This intronless gene encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of this gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.cite web | title = Entrez Gene: TACSTD2 tumor-associated calcium signal transducer 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4070| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Linnenbach AJ, Wojcierowski J, Wu SA, "et al." |title=Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 1 |pages= 27–31 |year= 1989 |pmid= 2911574 |doi=
*cite journal | author=Fornaro M, Dell'Arciprete R, Stella M, "et al." |title=Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. |journal=Int. J. Cancer |volume=62 |issue= 5 |pages= 610–8 |year= 1995 |pmid= 7665234 |doi=
*cite journal | author=Linnenbach AJ, Seng BA, Wu S, "et al." |title=Retroposition in a family of carcinoma-associated antigen genes. |journal=Mol. Cell. Biol. |volume=13 |issue= 3 |pages= 1507–15 |year= 1993 |pmid= 8382772 |doi=
*cite journal | author=El Sewedy T, Fornaro M, Alberti S |title=Cloning of the murine TROP2 gene: conservation of a PIP2-binding sequence in the cytoplasmic domain of TROP-2. |journal=Int. J. Cancer |volume=75 |issue= 2 |pages= 324–30 |year= 1998 |pmid= 9462726 |doi=
*cite journal | author=Ripani E, Sacchetti A, Corda D, Alberti S |title=Human Trop-2 is a tumor-associated calcium signal transducer. |journal=Int. J. Cancer |volume=76 |issue= 5 |pages= 671–6 |year= 1998 |pmid= 9610724 |doi=
*cite journal | author=Tsujikawa M, Kurahashi H, Tanaka T, "et al." |title=Identification of the gene responsible for gelatinous drop-like corneal dystrophy. |journal=Nat. Genet. |volume=21 |issue= 4 |pages= 420–3 |year= 1999 |pmid= 10192395 |doi= 10.1038/7759
*cite journal | author=Nakamura T, Nishida K, Dota A, "et al." |title=Gelatino-lattice corneal dystrophy: clinical features and mutational analysis. |journal=Am. J. Ophthalmol. |volume=129 |issue= 5 |pages= 665–6 |year= 2000 |pmid= 10844062 |doi=
*cite journal | author=Kinoshita S, Nishida K, Dota A, "et al." |title=Epithelial barrier function and ultrastructure of gelatinous drop-like corneal dystrophy. |journal=Cornea |volume=19 |issue= 4 |pages= 551–5 |year= 2000 |pmid= 10928776 |doi=
*cite journal | author=Tsujikawa M, Tsujikawa K, Maeda N, "et al." |title=Rapid detection of M1S1 mutations by the protein truncation test. |journal=Invest. Ophthalmol. Vis. Sci. |volume=41 |issue= 9 |pages= 2466–8 |year= 2000 |pmid= 10937555 |doi=
*cite journal | author=Ha NT, Fujiki K, Hotta Y, "et al." |title=Q118X mutation of M1S1 gene caused gelatinous drop-like corneal dystrophy: the P501T of BIGH3 gene found in a family with gelatinous drop-like corneal dystrophy. |journal=Am. J. Ophthalmol. |volume=130 |issue= 1 |pages= 119–20 |year= 2000 |pmid= 11004271 |doi=
*cite journal | author=Calabrese G, Crescenzi C, Morizio E, "et al." |title=Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=92 |issue= 1-2 |pages= 164–5 |year= 2001 |pmid= 11306819 |doi=
*cite journal | author=Tasa G, Kals J, Muru K, "et al." |title=A novel mutation in the M1S1 gene responsible for gelatinous droplike corneal dystrophy. |journal=Invest. Ophthalmol. Vis. Sci. |volume=42 |issue= 12 |pages= 2762–4 |year= 2001 |pmid= 11687514 |doi=
*cite journal | author=Yoshida S, Kumano Y, Yoshida A, "et al." |title=Two brothers with gelatinous drop-like dystrophy at different stages of the disease: role of mutational analysis. |journal=Am. J. Ophthalmol. |volume=133 |issue= 6 |pages= 830–2 |year= 2002 |pmid= 12036680 |doi=
*cite journal | author=Ren Z, Lin PY, Klintworth GK, "et al." |title=Allelic and locus heterogeneity in autosomal recessive gelatinous drop-like corneal dystrophy. |journal=Hum. Genet. |volume=110 |issue= 6 |pages= 568–77 |year= 2002 |pmid= 12107443 |doi= 10.1007/s00439-002-0729-z
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ha NT, Chau HM, Cung le X, "et al." |title=A novel mutation of M1S1 gene found in a Vietnamese patient with gelatinous droplike corneal dystrophy. |journal=Am. J. Ophthalmol. |volume=135 |issue= 3 |pages= 390–3 |year= 2003 |pmid= 12614764 |doi=
*cite journal | author=Gires O, Eskofier S, Lang S, "et al." |title=Cloning and characterisation of a 1.1 kb fragment of the carcinoma-associated epithelial cell adhesion molecule promoter. |journal=Anticancer Res. |volume=23 |issue= 4 |pages= 3255–61 |year= 2003 |pmid= 12926061 |doi=
*cite journal | author=Tian X, Fujiki K, Li Q, "et al." |title=Compound heterozygous mutations of M1S1 gene in gelatinous droplike corneal dystrophy. |journal=Am. J. Ophthalmol. |volume=137 |issue= 3 |pages= 567–9 |year= 2004 |pmid= 15013888 |doi= 10.1016/j.ajo.2003.08.008
*cite journal | author=Murakami A, Kimura S, Fujiki K, "et al." |title=Mutations in the membrane component, chromosome 1, surface marker 1 (M1S1) gene in gelatinous drop-like corneal dystrophy. |journal=Jpn. J. Ophthalmol. |volume=48 |issue= 4 |pages= 317–20 |year= 2004 |pmid= 15295654 |doi= 10.1007/s10384-003-0064-5
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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