APOBEC1

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1, also known as APOBEC1, is a human gene.cite web | title = Entrez Gene: APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=339| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.cite web | title = Entrez Gene: APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=339| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wedekind JE, Dance GS, Sowden MP, Smith HC |title=Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. |journal=Trends Genet. |volume=19 |issue= 4 |pages= 207–16 |year= 2003 |pmid= 12683974 |doi=
*cite journal | author=Harris RS, Liddament MT |title=Retroviral restriction by APOBEC proteins. |journal=Nat. Rev. Immunol. |volume=4 |issue= 11 |pages= 868–77 |year= 2004 |pmid= 15516966 |doi= 10.1038/nri1489
*cite journal | author=Espinosa R, Funahashi T, Hadjiagapiou C, "et al." |title=Assignment of the gene encoding the human apolipoprotein B mRNA editing enzyme (APOBEC1) to chromosome 12p13.1. |journal=Genomics |volume=24 |issue= 2 |pages= 414–5 |year= 1995 |pmid= 7698776 |doi= 10.1006/geno.1994.1645
*cite journal | author=Navaratnam N, Bhattacharya S, Fujino T, "et al." |title=Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site. |journal=Cell |volume=81 |issue= 2 |pages= 187–95 |year= 1995 |pmid= 7736571 |doi=
*cite journal | author=Lau PP, Zhu HJ, Baldini A, "et al." |title=Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 18 |pages= 8522–6 |year= 1994 |pmid= 8078915 |doi=
*cite journal | author=Hadjiagapiou C, Giannoni F, Funahashi T, "et al." |title=Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein. |journal=Nucleic Acids Res. |volume=22 |issue= 10 |pages= 1874–9 |year= 1994 |pmid= 8208612 |doi=
*cite journal | author=Morrison JR, Pászty C, Stevens ME, "et al." |title=Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 14 |pages= 7154–9 |year= 1996 |pmid= 8692961 |doi=
*cite journal | author=Lau PP, Zhu HJ, Nakamuta M, Chan L |title=Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 1452–5 |year= 1997 |pmid= 8999813 |doi=
*cite journal | author=Oka K, Kobayashi K, Sullivan M, "et al." |title=Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased low density lipoprotein in mice. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 1456–60 |year= 1997 |pmid= 8999814 |doi=
*cite journal | author=Hirano K, Min J, Funahashi T, "et al." |title=Characterization of the human apobec-1 gene: expression in gastrointestinal tissues determined by alternative splicing with production of a novel truncated peptide. |journal=J. Lipid Res. |volume=38 |issue= 5 |pages= 847–59 |year= 1997 |pmid= 9186903 |doi=
*cite journal | author=Fujino T, Navaratnam N, Scott J |title=Human apolipoprotein B RNA editing deaminase gene (APOBEC1). |journal=Genomics |volume=47 |issue= 2 |pages= 266–75 |year= 1998 |pmid= 9479499 |doi= 10.1006/geno.1997.5110
*cite journal | author=Mehta A, Kinter MT, Sherman NE, Driscoll DM |title=Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA. |journal=Mol. Cell. Biol. |volume=20 |issue= 5 |pages= 1846–54 |year= 2000 |pmid= 10669759 |doi=
*cite journal | author=Lellek H, Kirsten R, Diehl I, "et al." |title=Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex. |journal=J. Biol. Chem. |volume=275 |issue= 26 |pages= 19848–56 |year= 2000 |pmid= 10781591 |doi= 10.1074/jbc.M001786200
*cite journal | author=Blanc V, Navaratnam N, Henderson JO, "et al." |title=Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing. |journal=J. Biol. Chem. |volume=276 |issue= 13 |pages= 10272–83 |year= 2001 |pmid= 11134005 |doi= 10.1074/jbc.M006435200
*cite journal | author=Lau PP, Chang BH, Chan L |title=Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome. |journal=Biochem. Biophys. Res. Commun. |volume=282 |issue= 4 |pages= 977–83 |year= 2001 |pmid= 11352648 |doi= 10.1006/bbrc.2001.4679
*cite journal | author=Anant S, Henderson JO, Mukhopadhyay D, "et al." |title=Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. |journal=J. Biol. Chem. |volume=276 |issue= 50 |pages= 47338–51 |year= 2002 |pmid= 11577082 |doi= 10.1074/jbc.M104911200
*cite journal | author=Lau PP, Villanueva H, Kobayashi K, "et al." |title=A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing. |journal=J. Biol. Chem. |volume=276 |issue= 49 |pages= 46445–52 |year= 2002 |pmid= 11584023 |doi= 10.1074/jbc.M109215200
*cite journal | author=Anant S, Mukhopadhyay D, Sankaranand V, "et al." |title=ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing. |journal=Am. J. Physiol., Cell Physiol. |volume=281 |issue= 6 |pages= C1904–16 |year= 2001 |pmid= 11698249 |doi=
*cite journal | author=Mukhopadhyay D, Anant S, Lee RM, "et al." |title=C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme. |journal=Am. J. Hum. Genet. |volume=70 |issue= 1 |pages= 38–50 |year= 2002 |pmid= 11727199 |doi=
*cite journal | author=Dance GS, Sowden MP, Cartegni L, "et al." |title=Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing. |journal=J. Biol. Chem. |volume=277 |issue= 15 |pages= 12703–9 |year= 2002 |pmid= 11815617 |doi= 10.1074/jbc.M111337200

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