PLAGL1

Pleiomorphic adenoma gene-like 1, also known as PLAGL1, is a human gene.cite web | title = Entrez Gene: PLAGL1 pleiomorphic adenoma gene-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5325| accessdate = ]

PBB_Summary
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summary_text = This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Many transcript variants encoding two different isoforms have been found for this gene.cite web | title = Entrez Gene: PLAGL1 pleiomorphic adenoma gene-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5325| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Vernon M |title=Fifty years of research on the intelligence of deaf and hard-of-hearing children: a review of literature and discussion of implications. |journal=Journal of deaf studies and deaf education |volume=10 |issue= 3 |pages= 225–31 |year= 2005 |pmid= 15888725 |doi= 10.1093/deafed/eni024
*cite journal | author=Abdollahi A, Roberts D, Godwin AK, "et al." |title=Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors. |journal=Oncogene |volume=14 |issue= 16 |pages= 1973–9 |year= 1997 |pmid= 9150364 |doi= 10.1038/sj.onc.1201034
*cite journal | author=Abdollahi A, Godwin AK, Miller PD, "et al." |title=Identification of a gene containing zinc-finger motifs based on lost expression in malignantly transformed rat ovarian surface epithelial cells. |journal=Cancer Res. |volume=57 |issue= 10 |pages= 2029–34 |year= 1997 |pmid= 9158001 |doi=
*cite journal | author=Spengler D, Villalba M, Hoffmann A, "et al." |title=Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain. |journal=EMBO J. |volume=16 |issue= 10 |pages= 2814–25 |year= 1997 |pmid= 9184226 |doi= 10.1093/emboj/16.10.2814
*cite journal | author=Varrault A, Ciani E, Apiou F, "et al." |title=hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 15 |pages= 8835–40 |year= 1998 |pmid= 9671765 |doi=
*cite journal | author=Kas K, Voz ML, Hensen K, "et al." |title=Transcriptional activation capacity of the novel PLAG family of zinc finger proteins. |journal=J. Biol. Chem. |volume=273 |issue= 36 |pages= 23026–32 |year= 1998 |pmid= 9722527 |doi=
*cite journal | author=Abdollahi A, Bao R, Hamilton TC |title=LOT1 is a growth suppressor gene down-regulated by the epidermal growth factor receptor ligands and encodes a nuclear zinc-finger protein. |journal=Oncogene |volume=18 |issue= 47 |pages= 6477–87 |year= 2000 |pmid= 10597250 |doi= 10.1038/sj.onc.1203067
*cite journal | author=Kamiya M, Judson H, Okazaki Y, "et al." |title=The cell cycle control gene ZAC/PLAGL1 is imprinted--a strong candidate gene for transient neonatal diabetes. |journal=Hum. Mol. Genet. |volume=9 |issue= 3 |pages= 453–60 |year= 2000 |pmid= 10655556 |doi=
*cite journal | author=Bilanges B, Varrault A, Mazumdar A, "et al." |title=Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities. |journal=Oncogene |volume=20 |issue= 10 |pages= 1246–53 |year= 2001 |pmid= 11313869 |doi= 10.1038/sj.onc.1204237
*cite journal | author=Huang SM, Schönthal AH, Stallcup MR |title=Enhancement of p53-dependent gene activation by the transcriptional coactivator Zac1. |journal=Oncogene |volume=20 |issue= 17 |pages= 2134–43 |year= 2001 |pmid= 11360197 |doi= 10.1038/sj.onc.1204298
*cite journal | author=Mackay DJ, Coupe AM, Shield JP, "et al." |title=Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus. |journal=Hum. Genet. |volume=110 |issue= 2 |pages= 139–44 |year= 2002 |pmid= 11935319 |doi= 10.1007/s00439-001-0671-5
*cite journal | author=Abdollahi A, Pisarcik D, Roberts D, "et al." |title=LOT1 (PLAGL1/ZAC1), the candidate tumor suppressor gene at chromosome 6q24-25, is epigenetically regulated in cancer. |journal=J. Biol. Chem. |volume=278 |issue= 8 |pages= 6041–9 |year= 2003 |pmid= 12473647 |doi= 10.1074/jbc.M210361200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hoffmann A, Ciani E, Boeckardt J, "et al." |title=Transcriptional activities of the zinc finger protein Zac are differentially controlled by DNA binding. |journal=Mol. Cell. Biol. |volume=23 |issue= 3 |pages= 988–1003 |year= 2003 |pmid= 12529403 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Ma D, Shield JP, Dean W, "et al." |title=Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM. |journal=J. Clin. Invest. |volume=114 |issue= 3 |pages= 339–48 |year= 2004 |pmid= 15286800 |doi= 10.1172/JCI200419876
*cite journal | author=Cvetkovic D, Pisarcik D, Lee C, "et al." |title=Altered expression and loss of heterozygosity of the LOT1 gene in ovarian cancer. |journal=Gynecol. Oncol. |volume=95 |issue= 3 |pages= 449–55 |year= 2005 |pmid= 15581945 |doi= 10.1016/j.ygyno.2004.08.051
*cite journal | author=Mitchell J, Punthakee Z, Lo B, "et al." |title=Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search for the aetiology of a new autosomal recessive syndrome. |journal=Diabetologia |volume=47 |issue= 12 |pages= 2160–7 |year= 2005 |pmid= 15592663 |doi= 10.1007/s00125-004-1576-3

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