- FLOT1
Flotillin 1, also known as FLOT1, is a human
gene .cite web | title = Entrez Gene: FLOT1 flotillin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10211| accessdate = ]PBB_Summary
section_title =
summary_text = Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.cite web | title = Entrez Gene: FLOT1 flotillin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10211| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Bickel PE, Scherer PE, Schnitzer JE, "et al." |title=Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins. |journal=J. Biol. Chem. |volume=272 |issue= 21 |pages= 13793–802 |year= 1997 |pmid= 9153235 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Volonte D, Galbiati F, Li S, "et al." |title=Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe. |journal=J. Biol. Chem. |volume=274 |issue= 18 |pages= 12702–9 |year= 1999 |pmid= 10212252 |doi=
*cite journal | author=Hazarika P, Dham N, Patel P, "et al." |title=Flotillin 2 is distinct from epidermal surface antigen (ESA) and is associated with filopodia formation. |journal=J. Cell. Biochem. |volume=75 |issue= 1 |pages= 147–59 |year= 1999 |pmid= 10462713 |doi=
*cite journal | author=Hu RM, Han ZG, Song HD, "et al." |title=Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 17 |pages= 9543–8 |year= 2000 |pmid= 10931946 |doi= 10.1073/pnas.160270997
*cite journal | author=Baumann CA, Ribon V, Kanzaki M, "et al." |title=CAP defines a second signalling pathway required for insulin-stimulated glucose transport. |journal=Nature |volume=407 |issue= 6801 |pages= 202–7 |year= 2000 |pmid= 11001060 |doi= 10.1038/35025089
*cite journal | author=Zhang QH, Ye M, Wu XY, "et al." |title=Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. |journal=Genome Res. |volume=10 |issue= 10 |pages= 1546–60 |year= 2001 |pmid= 11042152 |doi=
*cite journal | author=Salzer U, Prohaska R |title=Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts. |journal=Blood |volume=97 |issue= 4 |pages= 1141–3 |year= 2001 |pmid= 11159550 |doi=
*cite journal | author=Edgar AJ, Polak JM |title=Flotillin-1: gene structure: cDNA cloning from human lung and the identification of alternative polyadenylation signals. |journal=Int. J. Biochem. Cell Biol. |volume=33 |issue= 1 |pages= 53–64 |year= 2001 |pmid= 11167132 |doi=
*cite journal | author=Kimura A, Baumann CA, Chiang SH, Saltiel AR |title=The sorbin homology domain: a motif for the targeting of proteins to lipid rafts. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 16 |pages= 9098–103 |year= 2001 |pmid= 11481476 |doi= 10.1073/pnas.151252898
*cite journal | author=Stuermer CA, Lang DM, Kirsch F, "et al." |title=Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2. |journal=Mol. Biol. Cell |volume=12 |issue= 10 |pages= 3031–45 |year= 2002 |pmid= 11598189 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Girardot N, Allinquant B, Duyckaerts C |title= [Lipid rafts, flotillin-1 and Alzheimer disease] |journal=J. Soc. Biol. |volume=197 |issue= 3 |pages= 223–9 |year= 2004 |pmid= 14708344 |doi=
*cite journal | author=Wakasugi K, Nakano T, Kitatsuji C, Morishima I |title=Human neuroglobin interacts with flotillin-1, a lipid raft microdomain-associated protein. |journal=Biochem. Biophys. Res. Commun. |volume=318 |issue= 2 |pages= 453–60 |year= 2004 |pmid= 15120622 |doi= 10.1016/j.bbrc.2004.04.045
*cite journal | author=Haglund K, Ivankovic-Dikic I, Shimokawa N, "et al." |title=Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites. |journal=J. Cell. Sci. |volume=117 |issue= Pt 12 |pages= 2557–68 |year= 2004 |pmid= 15128873 |doi= 10.1242/jcs.01148
*cite journal | author=Bared SM, Buechler C, Boettcher A, "et al." |title=Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells. |journal=Mol. Biol. Cell |volume=15 |issue= 12 |pages= 5399–407 |year= 2005 |pmid= 15469992 |doi= 10.1091/mbc.E04-03-0182
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Jacobowitz DM, Kallarakal AT |title=Flotillin-1 in the substantia nigra of the Parkinson brain and a predominant localization in catecholaminergic nerves in the rat brain. |journal=Neurotoxicity research |volume=6 |issue= 4 |pages= 245–57 |year= 2005 |pmid= 15545008 |doi=
*cite journal | author=Pope SN, Lee IR |title=Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. |journal=J. Steroid Biochem. Mol. Biol. |volume=94 |issue= 1-3 |pages= 203–8 |year= 2005 |pmid= 15862967 |doi= 10.1016/j.jsbmb.2005.01.007PBB_Controls
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