GNAZ

GNAZ

Guanine nucleotide binding protein (G protein), alpha z polypeptide, also known as GNAZ, is a human gene.cite web | title = Entrez Gene: GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2781| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of a G protein subfamily that mediates signal transduction in pertussis toxin-insensitive systms. This encoded protein may play a role in maintaining the ionic balance of perilymphatic and endolymphatic cochlear fluids.cite web | title = Entrez Gene: GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2781| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wilkie TM, Gilbert DJ, Olsen AS, "et al." |title=Evolution of the mammalian G protein alpha subunit multigene family. |journal=Nat. Genet. |volume=1 |issue= 2 |pages= 85–91 |year= 1993 |pmid= 1302014 |doi= 10.1038/ng0592-85
*cite journal | author=Jiang M, Pandey S, Tran VT, Fong HK |title=Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=88 |issue= 9 |pages= 3907–11 |year= 1991 |pmid= 1902575 |doi=
*cite journal | author=Gagnon AW, Manning DR, Catani L, "et al." |title=Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes. |journal=Blood |volume=78 |issue= 5 |pages= 1247–53 |year= 1991 |pmid= 1908722 |doi=
*cite journal | author=Matsuoka M, Itoh H, Kaziro Y |title=Characterization of the human gene for Gx alpha, a pertussis toxin-insensitive regulatory GTP-binding protein. |journal=J. Biol. Chem. |volume=265 |issue= 22 |pages= 13215–20 |year= 1990 |pmid= 2115889 |doi=
*cite journal | author=Hinton DR, Blanks JC, Fong HK, "et al." |title=Novel localization of a G protein, Gz-alpha, in neurons of brain and retina. |journal=J. Neurosci. |volume=10 |issue= 8 |pages= 2763–70 |year= 1990 |pmid= 2117645 |doi=
*cite journal | author=Mumby SM, Heukeroth RO, Gordon JI, Gilman AG |title=G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 2 |pages= 728–32 |year= 1990 |pmid= 2153964 |doi=
*cite journal | author=Matsuoka M, Itoh H, Kozasa T, Kaziro Y |title=Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 15 |pages= 5384–8 |year= 1988 |pmid= 2456569 |doi=
*cite journal | author=Blatt C, Eversole-Cire P, Cohn VH, "et al." |title=Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 20 |pages= 7642–6 |year= 1988 |pmid= 2902634 |doi=
*cite journal | author=Fong HK, Yoshimoto KK, Eversole-Cire P, Simon MI |title=Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 9 |pages= 3066–70 |year= 1988 |pmid= 3129724 |doi=
*cite journal | author=Fields TA, Casey PJ |title=Phosphorylation of Gz alpha by protein kinase C blocks interaction with the beta gamma complex. |journal=J. Biol. Chem. |volume=270 |issue= 39 |pages= 23119–25 |year= 1995 |pmid= 7559455 |doi=
*cite journal | author=Lounsbury KM, Schlegel B, Poncz M, "et al." |title=Analysis of Gz alpha by site-directed mutagenesis. Sites and specificity of protein kinase C-dependent phosphorylation. |journal=J. Biol. Chem. |volume=268 |issue= 5 |pages= 3494–8 |year= 1993 |pmid= 8429024 |doi=
*cite journal | author=Linder ME, Middleton P, Hepler JR, "et al." |title=Lipid modifications of G proteins: alpha subunits are palmitoylated. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 8 |pages= 3675–9 |year= 1993 |pmid= 8475115 |doi=
*cite journal | author=Hunt TW, Fields TA, Casey PJ, Peralta EG |title=RGS10 is a selective activator of G alpha i GTPase activity. |journal=Nature |volume=383 |issue= 6596 |pages= 175–7 |year= 1996 |pmid= 8774883 |doi= 10.1038/383175a0
*cite journal | author=Magovcevic I, Khetarpal U, Bieber FR, Morton CC |title=GNAZ in human fetal cochlea: expression, localization, and potential role in inner ear function. |journal=Hear. Res. |volume=90 |issue= 1-2 |pages= 55–64 |year= 1996 |pmid= 8975005 |doi=
*cite journal | author=De Vries L, Elenko E, Hubler L, "et al." |title=GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 26 |pages= 15203–8 |year= 1997 |pmid= 8986788 |doi=
*cite journal | author=Ho MK, Wong YH |title=Functional role of amino-terminal serine16 and serine27 of G alphaZ in receptor and effector coupling. |journal=J. Neurochem. |volume=68 |issue= 6 |pages= 2514–22 |year= 1997 |pmid= 9166747 |doi=
*cite journal | author=Sidhu A, Kimura K, Uh M, "et al." |title=Multiple coupling of human D5 dopamine receptors to guanine nucleotide binding proteins Gs and Gz. |journal=J. Neurochem. |volume=70 |issue= 6 |pages= 2459–67 |year= 1998 |pmid= 9603210 |doi=
*cite journal | author=Lin P, Le-Niculescu H, Hofmeister R, "et al." |title=The mammalian calcium-binding protein, nucleobindin (CALNUC), is a Golgi resident protein. |journal=J. Cell Biol. |volume=141 |issue= 7 |pages= 1515–27 |year= 1998 |pmid= 9647645 |doi=
*cite journal | author=Glick JL, Meigs TE, Miron A, Casey PJ |title=RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 26008–13 |year= 1998 |pmid= 9748279 |doi=

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