- CIB1
Calcium and integrin binding 1 (calmyrin), also known as CIB1, is a human
gene .cite web | title = Entrez Gene: CIB1 calcium and integrin binding 1 (calmyrin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10519| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3).cite web | title = Entrez Gene: CIB1 calcium and integrin binding 1 (calmyrin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10519| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Naik UP, Patel PM, Parise LV |title=Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain. |journal=J. Biol. Chem. |volume=272 |issue= 8 |pages= 4651–4 |year= 1997 |pmid= 9030514 |doi=
*cite journal | author=Wu X, Lieber MR |title=Interaction between DNA-dependent protein kinase and a novel protein, KIP. |journal=Mutat. Res. |volume=385 |issue= 1 |pages= 13–20 |year= 1997 |pmid= 9372844 |doi=
*cite journal | author=Seki N, Hayashi A, Abe M, "et al." |title=Chromosomal assignment of the gene for human DNA-PKcs interacting protein (KIP) on chromosome 15q25.3-q26.1 by somatic hybrid analysis and fluorescence in situ hybridization. |journal=J. Hum. Genet. |volume=43 |issue= 4 |pages= 275–7 |year= 1999 |pmid= 9852683 |doi=
*cite journal | author=Stabler SM, Ostrowski LL, Janicki SM, Monteiro MJ |title=A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein. |journal=J. Cell Biol. |volume=145 |issue= 6 |pages= 1277–92 |year= 1999 |pmid= 10366599 |doi=
*cite journal | author=Kauselmann G, Weiler M, Wulff P, "et al." |title=The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity. |journal=EMBO J. |volume=18 |issue= 20 |pages= 5528–39 |year= 1999 |pmid= 10523297 |doi= 10.1093/emboj/18.20.5528
*cite journal | author=Hwang PM, Vogel HJ |title=Structures of the platelet calcium- and integrin-binding protein and the alphaIIb-integrin cytoplasmic domain suggest a mechanism for calcium-regulated recognition; homology modelling and NMR studies. |journal=J. Mol. Recognit. |volume=13 |issue= 2 |pages= 83–92 |year= 2000 |pmid= 10822252 |doi= 10.1002/(SICI)1099-1352(200003/04)13:2<83::AID-JMR491>3.0.CO;2-A |doilabel=10.1002/(SICI)1099-1352(200003/04)13:283::AID-JMR4913.0.CO;2-A
*cite journal | author=Hattori A, Seki N, Hayashi A, "et al." |title=Genomic structure of mouse and human genes for DNA-PKcs interacting protein (KIP). |journal=DNA Seq. |volume=10 |issue= 6 |pages= 415–8 |year= 2000 |pmid= 10826701 |doi=
*cite journal | author=Holtrich U, Wolf G, Yuan J, "et al." |title=Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages. |journal=Oncogene |volume=19 |issue= 42 |pages= 4832–9 |year= 2000 |pmid= 11039900 |doi= 10.1038/sj.onc.1203845
*cite journal | author=Haataja L, Kaartinen V, Groffen J, Heisterkamp N |title=The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8321–8 |year= 2002 |pmid= 11756406 |doi= 10.1074/jbc.M105363200
*cite journal | author=Whitehouse C, Chambers J, Howe K, "et al." |title=NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube. |journal=Eur. J. Biochem. |volume=269 |issue= 2 |pages= 538–45 |year= 2002 |pmid= 11856312 |doi=
*cite journal | author=Hollenbach AD, McPherson CJ, Lagutina I, Grosveld G |title=The EF-hand calcium-binding protein calmyrin inhibits the transcriptional and DNA-binding activity of Pax3. |journal=Biochim. Biophys. Acta |volume=1574 |issue= 3 |pages= 321–8 |year= 2002 |pmid= 11997098 |doi=
*cite journal | author=Henderson MJ, Russell AJ, Hird S, "et al." |title=EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response. |journal=J. Biol. Chem. |volume=277 |issue= 29 |pages= 26468–78 |year= 2002 |pmid= 12011095 |doi= 10.1074/jbc.M203527200
*cite journal | author=Barry WT, Boudignon-Proudhon C, Shock DD, "et al." |title=Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain. |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 28877–83 |year= 2002 |pmid= 12023286 |doi= 10.1074/jbc.M202983200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ma S, Liu MA, Yuan YL, Erikson RL |title=The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB. |journal=Mol. Cancer Res. |volume=1 |issue= 5 |pages= 376–84 |year= 2003 |pmid= 12651910 |doi=
*cite journal | author=Naik UP, Naik MU |title=Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen. |journal=Blood |volume=102 |issue= 4 |pages= 1355–62 |year= 2003 |pmid= 12714504 |doi= 10.1182/blood-2003-02-0591
*cite journal | author=Naik MU, Naik UP |title=Calcium-and integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen. |journal=Blood |volume=102 |issue= 10 |pages= 3629–36 |year= 2004 |pmid= 12881299 |doi= 10.1182/blood-2003-05-1703
*cite journal | author=Yamniuk AP, Nguyen LT, Hoang TT, Vogel HJ |title=Metal ion binding properties and conformational states of calcium- and integrin-binding protein. |journal=Biochemistry |volume=43 |issue= 9 |pages= 2558–68 |year= 2004 |pmid= 14992593 |doi= 10.1021/bi035432b
*cite journal | author=Lee GE, Yu EY, Cho CH, "et al." |title=DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase. |journal=J. Biol. Chem. |volume=279 |issue= 33 |pages= 34750–5 |year= 2004 |pmid= 15190070 |doi= 10.1074/jbc.M401843200
*cite journal | author=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004PBB_Controls
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