CLIC1

Chloride intracellular channel 1, also known as CLIC1, is a human gene.cite web | title = Entrez Gene: CLIC1 chloride intracellular channel 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1192| accessdate = ]

PBB_Summary
section_title =
summary_text = Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.cite web | title = Entrez Gene: CLIC1 chloride intracellular channel 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1192| accessdate = ]

ee also

* Chloride channel

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Okubo K, Hori N, Matoba R, "et al." |title=Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression. |journal=Nat. Genet. |volume=2 |issue= 3 |pages= 173–9 |year= 1994 |pmid= 1345164 |doi= 10.1038/ng1192-173

*cite journal | author=Frigerio JM, Berthézène P, Garrido P, "et al." |title=Analysis of 2166 clones from a human colorectal cancer cDNA library by partial sequencing. |journal=Hum. Mol. Genet. |volume=4 |issue= 1 |pages= 37–43 |year= 1995 |pmid= 7711732 |doi=

*cite journal | author=Liew CC, Hwang DM, Fung YW, "et al." |title=A catalogue of genes in the cardiovascular system as identified by expressed sequence tags. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 22 |pages= 10645–9 |year= 1994 |pmid= 7938007 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Valenzuela SM, Martin DK, Por SB, "et al." |title=Molecular cloning and expression of a chloride ion channel of cell nuclei. |journal=J. Biol. Chem. |volume=272 |issue= 19 |pages= 12575–82 |year= 1997 |pmid= 9139710 |doi=
*cite journal | author=Heiss NS, Poustka A |title=Genomic structure of a novel chloride channel gene, CLIC2, in Xq28. |journal=Genomics |volume=45 |issue= 1 |pages= 224–8 |year= 1997 |pmid= 9339381 |doi= 10.1006/geno.1997.4922
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Tulk BM, Edwards JC |title=NCC27, a homolog of intracellular Cl- channel p64, is expressed in brush border of renal proximal tubule. |journal=Am. J. Physiol. |volume=274 |issue= 6 Pt 2 |pages= F1140–9 |year= 1998 |pmid= 9841507 |doi=
*cite journal | author=Chuang JZ, Milner TA, Zhu M, Sung CH |title=A 29 kDa intracellular chloride channel p64H1 is associated with large dense-core vesicles in rat hippocampal neurons. |journal=J. Neurosci. |volume=19 |issue= 8 |pages= 2919–28 |year= 1999 |pmid= 10191309 |doi=
*cite journal | author=Ribas G, Neville M, Wixon JL, "et al." |title=Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region. |journal=J. Immunol. |volume=163 |issue= 1 |pages= 278–87 |year= 1999 |pmid= 10384126 |doi=
*cite journal | author=Berryman M, Bretscher A |title=Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli. |journal=Mol. Biol. Cell |volume=11 |issue= 5 |pages= 1509–21 |year= 2000 |pmid= 10793131 |doi=
*cite journal | author=Tonini R, Ferroni A, Valenzuela SM, "et al." |title=Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells. |journal=FASEB J. |volume=14 |issue= 9 |pages= 1171–8 |year= 2000 |pmid= 10834939 |doi=
*cite journal | author=Valenzuela SM, Mazzanti M, Tonini R, "et al." |title=The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle. |journal=J. Physiol. (Lond.) |volume=529 Pt 3 |issue= |pages= 541–52 |year= 2001 |pmid= 11195932 |doi=
*cite journal | author=Harrop SJ, DeMaere MZ, Fairlie WD, "et al." |title=Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution. |journal=J. Biol. Chem. |volume=276 |issue= 48 |pages= 44993–5000 |year= 2002 |pmid= 11551966 |doi= 10.1074/jbc.M107804200
*cite journal | author=Warton K, Tonini R, Fairlie WD, "et al." |title=Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1. |journal=J. Biol. Chem. |volume=277 |issue= 29 |pages= 26003–11 |year= 2002 |pmid= 11978800 |doi= 10.1074/jbc.M203666200
*cite journal | author=Shanks RA, Larocca MC, Berryman M, "et al." |title=AKAP350 at the Golgi apparatus. II. Association of AKAP350 with a novel chloride intracellular channel (CLIC) family member. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40973–80 |year= 2002 |pmid= 12163479 |doi= 10.1074/jbc.M112277200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Fan L, Yu W, Zhu X |title=Interaction of Sedlin with chloride intracellular channel proteins. |journal=FEBS Lett. |volume=540 |issue= 1-3 |pages= 77–80 |year= 2003 |pmid= 12681486 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Littler DR, Harrop SJ, Fairlie WD, "et al." |title=The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition. |journal=J. Biol. Chem. |volume=279 |issue= 10 |pages= 9298–305 |year= 2004 |pmid= 14613939 |doi= 10.1074/jbc.M308444200
*cite journal | author=Singh H, Ashley RH |title=Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore. |journal=BIOPHYS. J.|volume=90 |issue= 5 |pages= 1628-1638 |year= 2006 |pmid= 16339885 |doi=
*cite journal | author=Singh H, Cousin MA, Ashley RH |title=Functional reconstitution of mammalian 'chloride intracellular channels' CLIC1, CLIC4 and CLIC5 reveals differential regulation by cytoskeletal actin. |journal=FEBS J.|volume=274 |issue= 24 |pages= 6306-6316 |year= 2007 |pmid= 18028448 |doi=

External links

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