BTG2

BTG family, member 2, also known as BTG2, is a human gene.cite web | title = Entrez Gene: BTG2 BTG family, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7832| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle.cite web | title = Entrez Gene: BTG2 BTG family, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7832| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Puisieux A, Magaud JP |title= [Mechanisms of BTG2 activity, a transcriptional target of p53: evidences and hypothesis.] |journal=Bulletin du cancer |volume=86 |issue= 4 |pages= 358–64 |year= 1999 |pmid= 10341341 |doi=
*cite journal | author=Tirone F |title=The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair? |journal=J. Cell. Physiol. |volume=187 |issue= 2 |pages= 155–65 |year= 2001 |pmid= 11267995 |doi= 10.1002/jcp.1062
*cite journal | author=Matsuda S, Rouault J, Magaud J, Berthet C |title=In search of a function for the TIS21/PC3/BTG1/TOB family. |journal=FEBS Lett. |volume=497 |issue= 2-3 |pages= 67–72 |year= 2001 |pmid= 11377414 |doi=
*cite journal | author=Fletcher BS, Lim RW, Varnum BC, "et al." |title=Structure and expression of TIS21, a primary response gene induced by growth factors and tumor promoters. |journal=J. Biol. Chem. |volume=266 |issue= 22 |pages= 14511–8 |year= 1991 |pmid= 1713584 |doi=
*cite journal | author=Lin WJ, Gary JD, Yang MC, "et al." |title=The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferase. |journal=J. Biol. Chem. |volume=271 |issue= 25 |pages= 15034–44 |year= 1996 |pmid= 8663146 |doi=
*cite journal | author=Montagnoli A, Guardavaccaro D, Starace G, Tirone F |title=Overexpression of the nerve growth factor-inducible PC3 immediate early gene is associated with growth inhibition. |journal=Cell Growth Differ. |volume=7 |issue= 10 |pages= 1327–36 |year= 1997 |pmid= 8891336 |doi=
*cite journal | author=Rouault JP, Falette N, Guéhenneux F, "et al." |title=Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway. |journal=Nat. Genet. |volume=14 |issue= 4 |pages= 482–6 |year= 1997 |pmid= 8944033 |doi= 10.1038/ng1296-482
*cite journal | author=Rouault JP, Prévôt D, Berthet C, "et al." |title=Interaction of BTG1 and p53-regulated BTG2 gene products with mCaf1, the murine homolog of a component of the yeast CCR4 transcriptional regulatory complex. |journal=J. Biol. Chem. |volume=273 |issue= 35 |pages= 22563–9 |year= 1998 |pmid= 9712883 |doi=
*cite journal | author=Walden PD, Lefkowitz GK, Ficazzola M, "et al." |title=Identification of genes associated with stromal hyperplasia and glandular atrophy of the prostate by mRNA differential display. |journal=Exp. Cell Res. |volume=245 |issue= 1 |pages= 19–26 |year= 1999 |pmid= 9828097 |doi= 10.1006/excr.1998.4237
*cite journal | author=Iacopetti P, Michelini M, Stuckmann I, "et al." |title=Expression of the antiproliferative gene TIS21 at the onset of neurogenesis identifies single neuroepithelial cells that switch from proliferative to neuron-generating division. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 8 |pages= 4639–44 |year= 1999 |pmid= 10200315 |doi=
*cite journal | author=Prévôt D, Voeltzel T, Birot AM, "et al." |title=The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation. |journal=J. Biol. Chem. |volume=275 |issue= 1 |pages= 147–53 |year= 2000 |pmid= 10617598 |doi=
*cite journal | author=Guardavaccaro D, Corrente G, Covone F, "et al." |title=Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcription. |journal=Mol. Cell. Biol. |volume=20 |issue= 5 |pages= 1797–815 |year= 2000 |pmid= 10669755 |doi=
*cite journal | author=Prévôt D, Morel AP, Voeltzel T, "et al." |title=Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway. |journal=J. Biol. Chem. |volume=276 |issue= 13 |pages= 9640–8 |year= 2001 |pmid= 11136725 |doi= 10.1074/jbc.M008201200
*cite journal | author=Lin WJ, Chang YF, Wang WL, Huang CY |title=Mitogen-stimulated TIS21 protein interacts with a protein-kinase-Calpha-binding protein rPICK1. |journal=Biochem. J. |volume=354 |issue= Pt 3 |pages= 635–43 |year= 2001 |pmid= 11237868 |doi=
*cite journal | author=Yoshida Y, Hosoda E, Nakamura T, Yamamoto T |title=Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex. |journal=Jpn. J. Cancer Res. |volume=92 |issue= 6 |pages= 592–6 |year= 2001 |pmid= 11429045 |doi=
*cite journal | author=Ficazzola MA, Fraiman M, Gitlin J, "et al." |title=Antiproliferative B cell translocation gene 2 protein is down-regulated post-transcriptionally as an early event in prostate carcinogenesis. |journal=Carcinogenesis |volume=22 |issue= 8 |pages= 1271–9 |year= 2001 |pmid= 11470758 |doi=
*cite journal | author=Duriez C, Falette N, Audoynaud C, "et al." |title=The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor gene. |journal=Gene |volume=282 |issue= 1-2 |pages= 207–14 |year= 2002 |pmid= 11814693 |doi=

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