HIST2H3C

Histone cluster 2, H3c, also known as HIST2H3C, is a human gene.cite web | title = Entrez Gene: HIST2H3C histone cluster 2, H3c| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=126961| accessdate = ]

PBB_Summary
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summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.cite web | title = Entrez Gene: HIST2H3C histone cluster 2, H3c| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=126961| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Marashi F, Helms S, Shiels A, "et al." |title=Enhancer-facilitated expression of prokaryotic and eukaryotic genes using human histone gene 5' regulatory sequences. |journal=Biochem. Cell Biol. |volume=64 |issue= 4 |pages= 277–89 |year= 1986 |pmid= 3013246 |doi=
*cite journal | author=Green L, Van Antwerpen R, Stein J, "et al." |title=A major human histone gene cluster on the long arm of chromosome 1. |journal=Science |volume=226 |issue= 4676 |pages= 838–40 |year= 1984 |pmid= 6494913 |doi=
*cite journal | author=Ohe Y, Iwai K |title=Human spleen histone H3. Isolation and amino acid sequence. |journal=J. Biochem. |volume=90 |issue= 4 |pages= 1205–11 |year= 1982 |pmid= 7309716 |doi=
*cite journal | author=Díaz-Jullien C, Pérez-Estévez A, Covelo G, Freire M |title=Prothymosin alpha binds histones in vitro and shows activity in nucleosome assembly assay. |journal=Biochim. Biophys. Acta |volume=1296 |issue= 2 |pages= 219–27 |year= 1996 |pmid= 8814229 |doi=
*cite journal | author=Albig W, Doenecke D |title=The human histone gene cluster at the D6S105 locus. |journal=Hum. Genet. |volume=101 |issue= 3 |pages= 284–94 |year= 1998 |pmid= 9439656 |doi=
*cite journal | author=El Kharroubi A, Piras G, Zensen R, Martin MA |title=Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. |journal=Mol. Cell. Biol. |volume=18 |issue= 5 |pages= 2535–44 |year= 1998 |pmid= 9566873 |doi=
*cite journal | author=Ahn J, Gruen JR |title=The genomic organization of the histone clusters on human 6p21.3. |journal=Mamm. Genome |volume=10 |issue= 7 |pages= 768–70 |year= 1999 |pmid= 10384058 |doi=
*cite journal | author=Goto H, Tomono Y, Ajiro K, "et al." |title=Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation. |journal=J. Biol. Chem. |volume=274 |issue= 36 |pages= 25543–9 |year= 1999 |pmid= 10464286 |doi=
*cite journal | author=Deng L, de la Fuente C, Fu P, "et al." |title=Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. |journal=Virology |volume=277 |issue= 2 |pages= 278–95 |year= 2001 |pmid= 11080476 |doi= 10.1006/viro.2000.0593
*cite journal | author=Lachner M, O'Carroll D, Rea S, "et al." |title=Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. |journal=Nature |volume=410 |issue= 6824 |pages= 116–20 |year= 2001 |pmid= 11242053 |doi= 10.1038/35065132
*cite journal | author=Shankaranarayanan P, Chaitidis P, Kühn H, Nigam S |title=Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene. |journal=J. Biol. Chem. |volume=276 |issue= 46 |pages= 42753–60 |year= 2001 |pmid= 11509556 |doi= 10.1074/jbc.M102626200
*cite journal | author=Deng L, Wang D, de la Fuente C, "et al." |title=Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. |journal=Virology |volume=289 |issue= 2 |pages= 312–26 |year= 2001 |pmid= 11689053 |doi= 10.1006/viro.2001.1129
*cite journal | author=Goto H, Yasui Y, Nigg EA, Inagaki M |title=Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. |journal=Genes Cells |volume=7 |issue= 1 |pages= 11–7 |year= 2002 |pmid= 11856369 |doi=
*cite journal | author=Marzluff WF, Gongidi P, Woods KR, "et al." |title=The human and mouse replication-dependent histone genes. |journal=Genomics |volume=80 |issue= 5 |pages= 487–98 |year= 2003 |pmid= 12408966 |doi=
*cite journal | author=Ganesan S, Silver DP, Greenberg RA, "et al." |title=BRCA1 supports XIST RNA concentration on the inactive X chromosome. |journal=Cell |volume=111 |issue= 3 |pages= 393–405 |year= 2002 |pmid= 12419249 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Goo YH, Sohn YC, Kim DH, "et al." |title=Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 1 |pages= 140–9 |year= 2003 |pmid= 12482968 |doi=
*cite journal | author=Preuss U, Landsberg G, Scheidtmann KH |title=Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase. |journal=Nucleic Acids Res. |volume=31 |issue= 3 |pages= 878–85 |year= 2003 |pmid= 12560483 |doi=
*cite journal | author=Yoon HG, Chan DW, Huang ZQ, "et al." |title=Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1. |journal=EMBO J. |volume=22 |issue= 6 |pages= 1336–46 |year= 2003 |pmid= 12628926 |doi= 10.1093/emboj/cdg120
*cite journal | author=Lusic M, Marcello A, Cereseto A, Giacca M |title=Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. |journal=EMBO J. |volume=22 |issue= 24 |pages= 6550–61 |year= 2004 |pmid= 14657027 |doi= 10.1093/emboj/cdg631

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