Inclusion compound

Inclusion compound

In host-guest chemistry an inclusion compound is a complex in which one chemical compound (the "host") forms a cavity in which molecules of a second "guest" compound are located. The definition of inclusion compounds is very broad, extending to channels formed between molecules in a crystal lattice in which guest molecules can fit. If the spaces in the host lattice are enclosed on all sides so that the guest species is ‘trapped’ as in a cage, the compound is known as a clathrate. In molecular encapsulation a guest molecule is actually trapped inside another molecule.

Cyclodextrin inclusion compounds

Inclusion complexes are formed between cyclodextrins and ferroceneref|1. When a solution of both compounds in a 2:1 ratio in water is boiled for 2 days and then allowed to rest for 10 hours at room temperature orange-yellow crystals form. X-ray diffraction analysis of these crystals reveal a 4:5 inclusion complex with 4 molecules of ferrocene included in the cavity of 4 cyclodextrine molecules and with the fifth ferrocene molecule sandwiched between two stacks of ferrocene - cyclodextrine dimers.

Cyclodextrin also forms inclusion compounds with fragrance moleculesref|2. As a result the fragrance molecules have a reduced vapor pressure and are more stable towards exposure to light and air. When incorporated into textiles the fragrance lasts much longer due to the slow-release action.

External links

* IUPAC Gold Book [http://www.iupac.org/goldbook/I02998.pdf definition]

References

* "A unique tetramer of 4:5 -cyclodextrin–ferrocene in the solid state" Yu Liu, Rui-Qin Zhong, Heng-Yi Zhang and Hai-Bin Song Chemical Communications, 2005, (17), 2211 - 2213 [http://www.rsc.org/publishing/journals/CC/article.asp?doi=b418220k Abstract]
* "Fragrance-release Property of β-Cyclodextrin Inclusion Compounds and their Application in Aromatherapy" C. X. Wang, Sh. L. Chen Journal of Industrial Textiles, Vol. 34, No. 3, 157-166 (2005) [http://jit.sagepub.com/cgi/content/short/34/3/157 Abstract]


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • inclusion complex — Chem. a solid solution in which molecules of one compound occupy places in the crystal lattice of another compound. Cf. adduct (def. 2). Also called inclusion compound. * * * …   Universalium

  • inclusion complex — Chem. a solid solution in which molecules of one compound occupy places in the crystal lattice of another compound. Cf. adduct (def. 2). Also called inclusion compound …   Useful english dictionary

  • compound — 1. In chemistry, a substance formed by the covalent or electrostatic union of two or more elements, generally differing entirely in physical characteristics from any of its components. 2. In pharmacy, denoting a preparation containing several… …   Medical dictionary

  • Inclusion — (Roget s Thesaurus) >Comprehension under, or reference to a class. < N PARAG:Inclusion >N GRP: N 1 Sgm: N 1 inclusion inclusion admission comprehension reception GRP: N 2 Sgm: N 2 composition composition &c.(inclusion in a compound) 54… …   English dictionary for students

  • inclusion complex — a compound in which molecules of one type are enclosed within cavities in the crystalline lattice of another substance …   Medical dictionary

  • Clathrate compound — Examples of host molecules. A clathrate, clathrate compound or cage compound is a chemical substance consisting of a lattice of one type of molecule trapping and containing a second type of molecule. The name clathrate complex used to refer only… …   Wikipedia

  • Hereditary inclusion body myopathy — Hereditary inclusion body myopathies (HIBM) are a heterogeneous group of genetic disorders which have different symptoms. Generally, they are neuromuscular disorders characterized by muscle weakness developing in young adults. Hereditary… …   Wikipedia

  • clathrate compound — a type of inclusion complex in which molecules of one type are trapped within cavities of another substance, such as within a crystalline lattice structure or large molecule; called also occlusion c. and clathrate …   Medical dictionary

  • clathrate compound — /klæθreɪt ˈkɒmpaʊnd/ (say klathrayt kompownd) noun an inclusion complex in which molecules of one substance are completely enclosed within the crystal lattice of the other, as argon within hydroquinone crystals …  

  • Cucurbituril — Computer models of Q5, Q6, and Q7. Top row is the view into the cavity and the bottom is the side view Cucurbiturils are methylene linked macrocyclic molecules made of glycoluril [=C4H2N4O2=] monomers. The oxygen atoms are located along the edges …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”