Polyphosphate-glucose phosphotransferase

In enzymology, a polyphosphate-glucose phosphotransferase (EC number|2.7.1.63) is an enzyme that catalyzes the chemical reaction

:(phosphate)n + D-glucose $ightleftharpoons$ (phosphate)n-1 + D-glucose 6-phosphate

Thus, the two substrates of this enzyme are (phosphate)n and D-glucose, whereas its two products are (phosphate)n-1 and D-glucose 6-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is polyphosphate:D-glucose 6-phosphotransferase. Other names in common use include polyphosphate glucokinase, polyphosphate-D-(+)-glucose-6-phosphotransferase, and polyphosphate-glucose 6-phosphotransferase. This enzyme participates in glycolysis / gluconeogenesis. It employs one cofactor, neutral salt.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1WOQ.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9033-50-5."

Gene Ontology (GO) codes