Glycerate kinase

In enzymology, a glycerate kinase (EC number|2.7.1.31) is an enzyme that catalyzes the chemical reaction

:ATP + (R)-glycerate $ightleftharpoons$ ADP + 3-phospho-(R)-glycerate

Thus, the two substrates of this enzyme are ATP and (R)-glycerate, whereas its two products are ADP and 3-phospho-(R)-glycerate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:(R)-glycerate 3-phosphotransferase. Other names in common use include glycerate kinase (phosphorylating), D-glycerate 3-kinase, D-glycerate kinase, glycerate-3-kinase, GK, D-glyceric acid kinase, and ATP:D-glycerate 2-phosphotransferase. This enzyme participates in 3 metabolic pathways: glycine, serine and threonine metabolism, glycerolipid metabolism, and glyoxylate and dicarboxylate metabolism.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1TO6, PDB link|1X3L, and PDB link|2B8N.

References

*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|9026-61-3."

Gene Ontology (GO) codes