Acetylglutamate kinase

In enzymology, an acetylglutamate kinase (EC number|2.7.2.8) is an enzyme that catalyzes the chemical reaction

:ATP + N-acetyl-L-glutamate $ightleftharpoons$ ADP + N-acetyl-L-glutamyl 5-phosphate

Thus, the two substrates of this enzyme are ATP and N-acetyl-L-glutamate, whereas its two products are ADP and N-acetyl-L-glutamyl 5-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:N-acetyl-L-glutamate 5-phosphotransferase. Other names in common use include N-acetylglutamate 5-phosphotransferase, acetylglutamate phosphokinase, N-acetylglutamate phosphokinase, N-acetylglutamate kinase, and N-acetylglutamic 5-phosphotransferase. This enzyme participates in urea cycle and metabolism of amino groups.

tructural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1GS5, PDB link|1GSJ, PDB link|1OH9, PDB link|1OHA, PDB link|1OHB, PDB link|2AP9, PDB link|2BTY, PDB link|2BUF, and PDB link|2RD5.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9027-58-1."

Gene Ontology (GO) codes