(Skp1-protein)-hydroxyproline N-acetylglucosaminyltransferase

In enzymology, a [Skp1-protein] -hydroxyproline N-acetylglucosaminyltransferase (EC number|2.4.1.229) is an enzyme that catalyzes the chemical reaction

:UDP-N-acetylglucosamine + [Skp₁-protein] -hydroxyproline $ightleftharpoons$ UDP + [Skp₁-protein] -O-(N-acetyl-D-glucosaminyl)hydroxyproline

Thus, the two substrates of this enzyme are UDP-N-acetylglucosamine and [Skp1-protein-hydroxyproline] , whereas its two products are UDP and [Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline] .

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine: [Skp1-protein] -hydroxyproline N-acetyl-D-glucosaminyl-transferase. Other names in common use include Skp1-HyPro GlcNAc-transferase, UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide, GlcNAc-transferase, UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase, and UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase.

References

*
*
*

External links