Galactosyldiacylglycerol alpha-2,3-sialyltransferase

In enzymology, a galactosyldiacylglycerol alpha-2,3-sialyltransferase (EC number|2.4.99.5) is an enzyme that catalyzes the chemical reaction

:CMP-N-acetylneuraminate + 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol $ightleftharpoons$ CMP + 1,2-diacyl-3- [3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl] -sn- glycerol

Thus, the two substrates of this enzyme are CMP-N-acetylneuraminate and 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol, whereas its 3 products are CMP, [1,2-diacyl-3- [3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl] -sn-] , and glycerol.

This enzyme belongs to the family of transferases, specifically those glycosyltransferases that do not transfer hexosyl or pentosyl groups. The systematic name of this enzyme class is CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase. This enzyme participates in glycerolipid metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|80237-98-5."

Gene Ontology (GO) codes