Phosphatidylcholine-sterol O-acyltransferase
- Phosphatidylcholine-sterol O-acyltransferase
In enzymology, a phosphatidylcholine---sterol O-acyltransferase (EC number|2.3.1.43) is an enzyme that catalyzes the chemical reaction
:phosphatidylcholine + a sterol 1-acylglycerophosphocholine + a sterol ester
Thus, the two substrates of this enzyme are phosphatidylcholine and sterol, whereas its two products are 1-acylglycerophosphocholine and sterol ester.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is phosphatidylcholine:sterol O-acyltransferase. Other names in common use include lecithin---cholesterol acyltransferase, phospholipid---cholesterol acyltransferase, LCAT (lecithin-cholesterol acyltransferase), lecithin:cholesterol acyltransferase, and lysolecithin acyltransferase. This enzyme participates in glycerophospholipid metabolism.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9031-14-5."
Gene Ontology (GO) codes
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Look at other dictionaries:
phosphatidylcholine–sterol O-acyltransferase — phos·pha·ti·dyl·cho·line–ster·ol O ac·yl·trans·fer·ase (fos″fə ti″dəl koґlēn sterґol a″səl transґfər ās) [EC 2.3.1.43] an enzyme of the transferase class, secreted by the liver, that catalyzes the … Medical dictionary
Lecithin-cholesterol acyltransferase — (LCAT, also called phosphatidylcholine sterol O acyltransferase) is an enzyme which converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol) which is then sequestered into the core of a lipoprotein particle… … Wikipedia
List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… … Wikipedia
lipid — /lip id, luy pid/, n. Biochem. any of a group of organic compounds that are greasy to the touch, insoluble in water, and soluble in alcohol and ether: lipids comprise the fats and other esters with analogous properties and constitute, with… … Universalium
