Acetylornithine deacetylase

Acetylornithine deacetylase

In enzymology, an acetylornithine deacetylase (EC number| is an enzyme that catalyzes the chemical reaction

:N2-acetyl-L-ornithine + H2O ightleftharpoons acetate + L-ornithine

Thus, the two substrates of this enzyme are N2-acetyl-L-ornithine and H2O, whereas its two products are acetate and L-ornithine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N2-acetyl-L-ornithine amidohydrolase. Other names in common use include acetylornithinase, N-acetylornithinase, and 2-N-acetyl-L-ornithine amidohydrolase. This enzyme participates in urea cycle and metabolism of amino groups.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|2F7V and PDB link|2F8H.



External links

::"The CAS registry number for this enzyme class is CAS registry|9025-12-1."

Gene Ontology (GO) codes

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