Alpha-glucuronidase

In enzymology, an alpha-glucuronidase (EC number|3.2.1.139) is an enzyme that catalyzes the chemical reaction

:an alpha-D-glucuronoside + H₂O $ightleftharpoons$ an alcohol + D-glucuronate

Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H₂O, whereas its two products are alcohol and D-glucuronate.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase.

tructural studies

As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1GQI, PDB link|1GQJ, PDB link|1GQK, PDB link|1GQL, PDB link|1H41, PDB link|1K9D, PDB link|1K9E, PDB link|1K9F, PDB link|1L8N, PDB link|1MQP, PDB link|1MQQ, PDB link|1MQR, and PDB link|1VJT.

References

* Visser, J., Kusters van Someren, M.A., Beldman, G. and Voragen, A.G.J. (Eds.), Xylans and Xylanases, Elsevier, Amsterdam, 1992, p. 213-224.
*

External links

::"The CAS registry number for this enzyme class is CAS registry|37259-81-7."

Gene Ontology (GO) codes