Histidinol-phosphatase

In enzymology, a histidinol-phosphatase (EC number|3.1.3.15) is an enzyme that catalyzes the chemical reaction

:L-histidinol phosphate + H₂O $ightleftharpoons$ L-histidinol + phosphate

Thus, the two substrates of this enzyme are L-histidinol phosphate and H₂O, whereas its two products are L-histidinol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is L-histidinol-phosphate phosphohydrolase. Other names in common use include histidinol phosphate phosphatase, L-histidinol phosphate phosphatase, histidinolphosphate phosphatase, HPpase, and histidinolphosphatase. This enzyme participates in histidine metabolism.

tructural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2FPR, PDB link|2FPS, PDB link|2FPU, PDB link|2FPW, and PDB link|2FPX.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9025-79-0."

Gene Ontology (GO) codes