DGTPase

In enzymology, a dGTPase (EC number|3.1.5.1) is an enzyme that catalyzes the chemical reaction

:dGTP + H₂O $ightleftharpoons$ deoxyguanosine + triphosphate

Thus, the two substrates of this enzyme are dGTP and H₂O, whereas its two products are deoxyguanosine and triphosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on triphosphoric monoester bonds. The systematic name of this enzyme class is dGTP triphosphohydrolase. Other names in common use include deoxy-GTPase, deoxyguanosine 5-triphosphate triphosphohydrolase, deoxyguanosine triphosphatase, and deoxyguanosine triphosphate triphosphohydrolase. This enzyme participates in purine metabolism.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1HA3, PDB link|2C77, PDB link|2C78, and PDB link|2DQB.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9025-63-2."

Gene Ontology (GO) codes