2',3'-cyclic-nucleotide 3'-phosphodiesterase
- 2',3'-cyclic-nucleotide 3'-phosphodiesterase
In enzymology, a 2',3'-cyclic-nucleotide 3'-phosphodiesterase (EC number|3.1.4.37) is an enzyme that catalyzes the chemical reaction
:nucleoside 2',3'-cyclic phosphate + H2O nucleoside 2'-phosphate
Thus, the two substrates of this enzyme are nucleoside 2',3'-cyclic phosphate and H2O, whereas its product is nucleoside 2'-phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase. Other names in common use include cyclic-CMP phosphodiesterase, 2',3'-cyclic AMP phosphodiesterase, cyclic 2',3'-nucleotide 3'-phosphodiesterase, cyclic 2',3'-nucleotide phosphodiesterase, 2',3'-cyclic nucleoside monophosphate phosphodiesterase, 2',3'-cyclic nucleotide 3'-phosphohydrolase, CNPase, 2',3'-cyclic nucleotide phosphohydrolase, 2':3'-cyclic nucleotide 3'-phosphodiesterase, and 2':3'-CNMP-3'-ase.
tructural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1WOJ, PDB link|2I3E, and PDB link|2ILX.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|60098-35-3."
Gene Ontology (GO) codes
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