- Guanosine-5'-triphosphate,3'-diphosphate diphosphatase
In
enzymology , a guanosine-5'-triphosphate,3'-diphosphate diphosphatase (EC number|3.6.1.40) is anenzyme that catalyzes thechemical reaction :guanosine 5'-triphosphate,3'-diphosphate + H2O guanosine 5'-diphosphate,3'-diphosphate + phosphate
Thus, the two substrates of this enzyme are
guanosine 5'-triphosphate,3'-diphosphate and H2O, whereas its two products areguanosine 5'-diphosphate,3'-diphosphate andphosphate .This enzyme belongs to the family of
hydrolase s, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase. Other names in common use include pppGpp 5'-phosphohydrolase, guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase, guanosine pentaphosphatase, guanosine pentaphosphate phosphatase, guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase, and guanosine pentaphosphate phosphohydrolase. This enzyme participates inpurine metabolism .tructural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1T6C and PDB link|1T6D.
References
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External links
::"The
CAS registry number for this enzyme class is CAS registry|85130-44-5."Gene Ontology (GO) codes
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