- Fluid compartments
Fluid compartments in the
mammal ian body broadly comprise two compartments, each with several subdivisions:intracellular fluid , which makes up approximately 60-65% of body water, andextracellular fluid , which makes up the other 35-40% of body water. (For all practical purposes, the onlysolvent in the body iswater ) [cite web
last=Patlak
first=Joe
url= http://physioweb.med.uvm.edu/bodyfluids/the.htm
title="Body Fluids, Medical Physiology" ]Intracellular fluid
Intracellular fluid is found inside the bilayeredplasma membrane , and is the matrix in which cellularorganelles are suspended, andchemical reactions take place. [W.Kapit ,R.Macey,E.Meisami , "The Physiology Coloring Book 2nd ed" pg 1-7. Addison/Wesley/Longman, Inc.San Francisco ,2000.] The intracellular compartment contains on average about 28 liters of fluid, and under ordinary circumstances remains inosmotic equilibrium with the ECF.Extracellular fluid
Extravascular compartment
Outside the plasma membrane the cell is continually bathed in
interstitial fluid ,which is the immediatemicroenvironment that allows for movement ofions ,proteins andnutrients across the cell barrier. This fluid is not static, but is continally being refreshed and recollected bylymph atic channels. In the average male (70kg)human body, the interstitial space has approximately 11 liters of fluid.Intravascular compartment
The main intravascular fluid in mammals is
blood which is a complex fluid with elements of a suspension (blood cells),colloid (globulins) andsolvent (glucose and ions).The average volume of plasma in the average (70kg) male is approximately 3liters.The volume of the intravascular lumen is regulated in part by hydrostatic pressure gradients,and by readsorbtion by the kidneys.References
Intravascular compartmentThe main intravascular fluid in mammals is blood which is a complex fluid with elements of a suspension (blood cells), colloid(globulins) and solvent(glucose and ions).The average volume of plasma in the average (70kg) male is approximately 3 liters.The volume of the intravascular lumen is regulated in part by hydrostatic pressure gradients,and by reabsorbtion by the kidneys.
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