INPPL1

Inositol polyphosphate phosphatase-like 1, also known as INPPL1, is a human gene.cite web | title = Entrez Gene: INPPL1 inositol polyphosphate phosphatase-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3636| accessdate = ]

PBB_Summary
section_title =
summary_text = INPPL1 encodes inositol polyphosphate-5 phosphatase-like 1, a protein that in addition to the phosphatase domain contains an SH2 (src-homology domain 2) motif.cite web | title = Entrez Gene: INPPL1 inositol polyphosphate phosphatase-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3636| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hejna JA, Saito H, Merkens LS, "et al." |title=Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases. |journal=Genomics |volume=29 |issue= 1 |pages= 285–7 |year= 1996 |pmid= 8530088 |doi= 10.1006/geno.1995.1247
*cite journal | author=Pesesse X, Deleu S, De Smedt F, "et al." |title=Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP. |journal=Biochem. Biophys. Res. Commun. |volume=239 |issue= 3 |pages= 697–700 |year= 1997 |pmid= 9367831 |doi= 10.1006/bbrc.1997.7538
*cite journal | author=Habib T, Hejna JA, Moses RE, Decker SJ |title=Growth factors and insulin stimulate tyrosine phosphorylation of the 51C/SHIP2 protein. |journal=J. Biol. Chem. |volume=273 |issue= 29 |pages= 18605–9 |year= 1998 |pmid= 9660833 |doi=
*cite journal | author=Pesesse X, Moreau C, Drayer AL, "et al." |title=The SH2 domain containing inositol 5-phosphatase SHIP2 displays phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity. |journal=FEBS Lett. |volume=437 |issue= 3 |pages= 301–3 |year= 1998 |pmid= 9824312 |doi=
*cite journal | author=Wisniewski D, Strife A, Swendeman S, "et al." |title=A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells. |journal=Blood |volume=93 |issue= 8 |pages= 2707–20 |year= 1999 |pmid= 10194451 |doi=
*cite journal | author=Bruyns C, Pesesse X, Moreau C, "et al." |title=The two SH2-domain-containing inositol 5-phosphatases SHIP1 and SHIP2 are coexpressed in human T lymphocytes. |journal=Biol. Chem. |volume=380 |issue= 7-8 |pages= 969–74 |year= 1999 |pmid= 10494849 |doi=
*cite journal | author=Schurmans S, Carrió R, Behrends J, "et al." |title=The mouse SHIP2 (Inppl1) gene: complementary DNA, genomic structure, promoter analysis, and gene expression in the embryo and adult mouse. |journal=Genomics |volume=62 |issue= 2 |pages= 260–71 |year= 2000 |pmid= 10610720 |doi= 10.1006/geno.1999.5995
*cite journal | author=Muraille E, Bruhns P, Pesesse X, "et al." |title=The SH2 domain containing inositol 5-phosphatase SHIP2 associates to the immunoreceptor tyrosine-based inhibition motif of Fc gammaRIIB in B cells under negative signaling. |journal=Immunol. Lett. |volume=72 |issue= 1 |pages= 7–15 |year= 2000 |pmid= 10789675 |doi=
*cite journal | author=Prasad N, Topping RS, Decker SJ |title=SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading. |journal=Mol. Cell. Biol. |volume=21 |issue= 4 |pages= 1416–28 |year= 2001 |pmid= 11158326 |doi= 10.1128/MCB.21.4.1416-1428.2001
*cite journal | author=Wada T, Sasaoka T, Funaki M, "et al." |title=Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity. |journal=Mol. Cell. Biol. |volume=21 |issue= 5 |pages= 1633–46 |year= 2001 |pmid= 11238900 |doi= 10.1128/MCB.21.5.1633-1646.2001
*cite journal | author=Pesesse X, Dewaste V, De Smedt F, "et al." |title=The Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cells. |journal=J. Biol. Chem. |volume=276 |issue= 30 |pages= 28348–55 |year= 2001 |pmid= 11349134 |doi= 10.1074/jbc.M103537200
*cite journal | author=Dyson JM, O'Malley CJ, Becanovic J, "et al." |title=The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin. |journal=J. Cell Biol. |volume=155 |issue= 6 |pages= 1065–79 |year= 2002 |pmid= 11739414 |doi= 10.1083/jcb.200104005
*cite journal | author=Marion E, Kaisaki PJ, Pouillon V, "et al." |title=The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man. |journal=Diabetes |volume=51 |issue= 7 |pages= 2012–7 |year= 2002 |pmid= 12086927 |doi=
*cite journal | author=Giuriato S, Blero D, Robaye B, "et al." |title=SHIP2 overexpression strongly reduces the proliferation rate of K562 erythroleukemia cell line. |journal=Biochem. Biophys. Res. Commun. |volume=296 |issue= 1 |pages= 106–10 |year= 2002 |pmid= 12147234 |doi=
*cite journal | author=Prasad N, Topping RS, Decker SJ |title=Src family tyrosine kinases regulate adhesion-dependent tyrosine phosphorylation of 5'-inositol phosphatase SHIP2 during cell attachment and spreading on collagen I. |journal=J. Cell. Sci. |volume=115 |issue= Pt 19 |pages= 3807–15 |year= 2003 |pmid= 12235291 |doi=
*cite journal | author=Tridandapani S, Wang Y, Marsh CB, Anderson CL |title=Src homology 2 domain-containing inositol polyphosphate phosphatase regulates NF-kappa B-mediated gene transcription by phagocytic Fc gamma Rs in human myeloid cells. |journal=J. Immunol. |volume=169 |issue= 8 |pages= 4370–8 |year= 2002 |pmid= 12370370 |doi=
*cite journal | author=Vandenbroere I, Paternotte N, Dumont JE, "et al." |title=The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2. |journal=Biochem. Biophys. Res. Commun. |volume=300 |issue= 2 |pages= 494–500 |year= 2003 |pmid= 12504111 |doi=
*cite journal | author=Salomon AR, Ficarro SB, Brill LM, "et al." |title=Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 2 |pages= 443–8 |year= 2003 |pmid= 12522270 |doi= 10.1073/pnas.2436191100
*cite journal | author=Pengal RA, Ganesan LP, Fang H, "et al." |title=SHIP-2 inositol phosphatase is inducibly expressed in human monocytes and serves to regulate Fcgamma receptor-mediated signaling. |journal=J. Biol. Chem. |volume=278 |issue= 25 |pages= 22657–63 |year= 2003 |pmid= 12690104 |doi= 10.1074/jbc.M302907200
*cite journal | author=Kaisaki PJ, Delépine M, Woon PY, "et al." |title=Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome. |journal=Diabetes |volume=53 |issue= 7 |pages= 1900–4 |year= 2004 |pmid= 15220217 |doi=

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