Oleate hydratase

Oleate hydratase
oleate hydratase
Identifiers
EC number 4.2.1.53
CAS number 9073-51-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an oleate hydratase (EC 4.2.1.53) is an enzyme that catalyzes the chemical reaction

(R)-10-hydroxystearate \rightleftharpoons oleate + H2O

Hence, this enzyme has one substrate, (R)-10-hydroxystearate, and two products, oleate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (R)-10-hydroxystearate 10-hydro-lyase (oleate-forming). This enzyme is also called (R)-10-hydroxystearate 10-hydro-lyase.

References

  • Davis EN, Wallen LL, Goodwin JC, Rohwedder WK, Rhodes RA (1969). "Microbial hydration of cis-9-alkenoic acids". Lipids. 4 (5): 356–62. doi:10.1007/BF02531006. PMID 5823715. 
  • Gotouda H, Takatori T, Terazawa K, Nagao M, Tarao H (1988). "The mechanism of experimental adipocere formation: hydration and dehydrogenation in microbial synthesis of hydroxy and oxo fatty acids". Forensic. Sci. Int. 37 (4): 249–57. doi:10.1016/0379-0738(88)90233-2. PMID 3410394. 
  • Jr; Torkelson, A; Kisic, A; Bednarczyk, DJ; Schroepfer Jr, GJ (1970). "Stereospecific hydration of the delta-9 double bond of oleic acid". J. Biol. Chem. 245 (15): 3790–7. PMID 5492948. 
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