- Maleate hydratase
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maleate hydratase Identifiers EC number 4.2.1.31 CAS number 37290-71-4 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a maleate hydratase (EC 4.2.1.31) is an enzyme that catalyzes the chemical reaction
- (R)-malate maleate + H2O
Hence, this enzyme has one substrate, (R)-malate, and two products, maleate and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (R)-malate hydro-lyase (maleate-forming). Other names in common use include D-malate hydro-lyase, malease, and (R)-malate hydro-lyase. This enzyme participates in butanoate metabolism.
References
- Britten JS, Morell H, Taggart JV (1969). "Anion activation of maleate hydratase". Biochim. Biophys. Acta. 185 (1): 220–7. PMID 5796106.
- SACKS W, JENSEN CO (1951). "Malease, a hydrase from corn kernels". J. Biol. Chem. 192 (1): 231–6. PMID 14917669.
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