D-fuconate dehydratase

D-fuconate dehydratase
D-fuconate dehydratase
Identifiers
EC number 4.2.1.67
CAS number 9076-59-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a D-fuconate dehydratase (EC 4.2.1.67) is an enzyme that catalyzes the chemical reaction

D-fuconate \rightleftharpoons 2-dehydro-3-deoxy-D-fuconate + H2O

Hence, this enzyme has one substrate, D-fuconate, and two products, 2-dehydro-3-deoxy-D-fuconate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming). This enzyme is also called D-fuconate hydro-lyase. This enzyme participates in fructose and mannose metabolism.

References

  • Dahms AS, Anderson RL (1972). "D-Fucose metabolism in a pseudomonad. 3. Conversion of D-fuconate to 2-keto-3-deoxy-D-fuconate by a dehydratase". J. Biol. Chem. 247 (7): 2233–7. PMID 4335868.