- 3-hydroxypalmitoyl-(acyl-carrier-protein) dehydratase
In
enzymology , a 3-hydroxypalmitoyl- [acyl-carrier-protein] dehydratase (EC number|4.2.1.61) is anenzyme that catalyzes thechemical reaction :(3R)-3-hydroxypalmitoyl- [acyl-carrier-protein] ightleftharpoons hexadec-2-enoyl- [acyl-carrier-protein] + H2O
Hence, this enzyme has one substrate, [(3R)-3-hydroxypalmitoyl- [acyl-carrier-protein] , and two products, [hexadec-2-enoyl- [acyl-carrier-protein] and H2O.
This enzyme belongs to the family of
lyase s, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (3R)-3-hydroxypalmitoyl- [acyl-carrier-protein] hydro-lyase (hexadec-2-enoyl- [acyl-carrier protein] -forming). Other names in common use include D-3-hydroxypalmitoyl- [acyl-carrier-protein] dehydratase, beta-hydroxypalmitoyl-acyl carrier protein dehydrase, beta-hydroxypalmitoyl thioester dehydratase, beta-hydroxypalmityl-ACP dehydrase, and (3R)-3-hydroxypalmitoyl- [acyl-carrier-protein] hydro-lyase. This enzyme participates infatty acid biosynthesis .tructural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2PFF.
References
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External links
::"The
CAS registry number for this enzyme class is CAS registry|9030-86-8."Gene Ontology (GO) codes
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