3-hydroxybutyryl-CoA dehydratase

In enzymology, a 3-hydroxybutyryl-CoA dehydratase (EC number|4.2.1.55) is an enzyme that catalyzes the chemical reaction

:(3R)-3-hydroxybutanoyl-CoA $ightleftharpoons$ crotonoyl-CoA + H₂O

Hence, this enzyme has one substrate, (3R)-3-hydroxybutanoyl-CoA, and two products, crotonoyl-CoA and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming). Other names in common use include D-3-hydroxybutyryl coenzyme A dehydratase, D-3-hydroxybutyryl-CoA dehydratase, enoyl coenzyme A hydrase (D), and (3R)-3-hydroxybutanoyl-CoA hydro-lyase. This enzyme participates in butanoate metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37290-82-7."

Gene Ontology (GO) codes