Trypanothione synthase

In enzymology, a trypanothione synthase (EC number|6.3.1.9) is an enzyme that catalyzes the chemical reaction

:glutathione + glutathionylspermidine + ATP $ightleftharpoons$ N₁,N₈-bis(glutathionyl)spermidine + ADP + phosphate

The 3 substrates of this enzyme are glutathione, glutathionylspermidine, and ATP, whereas its 3 products are N1,N8-bis(glutathionyl)spermidine, ADP, and phosphate.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is glutathionylspermidine:glutathione ligase (ADP-forming).

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|130246-69-4."

Gene Ontology (GO) codes