- Isocitrate lyase
In
enzymology , an isocitrate lyase (EC number|4.1.3.1) is anenzyme that catalyzes thechemical reaction :isocitrate succinate + glyoxylate
Hence, this enzyme has one substrate,
isocitrate , and two products,succinate andglyoxylate .This enzyme belongs to the family of
lyase s, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is isocitrate glyoxylate-lyase (succinate-forming). Other names in common use include isocitrase, isocitritase, isocitratase, threo-Ds-isocitrate glyoxylate-lyase, and isocitrate glyoxylate-lyase. This enzyme participates inglyoxylate and dicarboxylate metabolism .tructural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1DQU, PDB link|1F61, PDB link|1F8I, PDB link|1F8M, and PDB link|1IGW.
References
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*External links
::"The
CAS registry number for this enzyme class is CAS registry|9045-78-7."Gene Ontology (GO) codes
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