2,6-dioxo-6-phenylhexa-3-enoate hydrolase

2,6-dioxo-6-phenylhexa-3-enoate hydrolase

In enzymology, a 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC number|3.7.1.8) is an enzyme that catalyzes the chemical reaction

:2,6-dioxo-6-phenylhexa-3-enoate + H2O ightleftharpoons benzoate + 2-oxopent-4-enoate

Thus, the two substrates of this enzyme are 2,6-dioxo-6-phenylhexa-3-enoate and H2O, whereas its two products are benzoate and 2-oxopent-4-enoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase. This enzyme is also called HOHPDA hydrolase. This enzyme participates in biphenyl degradation and fluorene degradation.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1C4X, PDB link|1J1I, and PDB link|2OG1.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|102925-38-2."

Gene Ontology (GO) codes


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