Thiosulfate sulfurtransferase
- Thiosulfate sulfurtransferase
In enzymology, a thiosulfate sulfurtransferase (EC number|2.8.1.1) is an enzyme that catalyzes the chemical reaction
:thiosulfate + cyanide sulfite + thiocyanate
Thus, the two substrates of this enzyme are thiosulfate and cyanide, whereas its two products are sulfite and thiocyanate.
This enzyme belongs to the family of transferases, specifically the sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:cyanide sulfurtransferase. Other names in common use include thiosulfate cyanide transsulfurase, thiosulfate thiotransferase, rhodanese, and rhodanase.
tructural studies
As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1BOH, PDB link|1BOI, PDB link|1DP2, PDB link|1E0C, PDB link|1H4K, PDB link|1H4M, PDB link|1ORB, PDB link|1RHD, PDB link|1RHS, PDB link|1UAR, and PDB link|2ORA.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9026-04-4."
Gene Ontology (GO) codes
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thiosulfate sulfurtransferase — thio·sul·fate sul·fur·trans·fer·ase (thi o sulґfāt sul″fər transґfər ās) [EC 2.8.1.1] a mitochondrial enzyme of the transferase class that catalyzes the conversion of cyanide to thiocyanate, using thiosulfate as a sulfur … Medical dictionary
Thiosulfate-thiol sulfurtransferase — In enzymology, a thiosulfate thiol sulfurtransferase (EC number|2.8.1.3) is an enzyme that catalyzes the chemical reaction:thiosulfate + 2 glutathione ightleftharpoons sulfite + glutathione disulfide + sulfideThus, the two substrates of this… … Wikipedia
Thiosulfate-dithiol sulfurtransferase — In enzymology, a thiosulfate dithiol sulfurtransferase (EC number|2.8.1.5) is an enzyme that catalyzes the chemical reaction:thiosulfate + dithioerythritol ightleftharpoons sulfite + 4,5 cis dihydroxy 1,2 dithiacyclohexane (i.e. oxidized… … Wikipedia
thiosulfate — S2O3=; the anion of thiosulfuric acid; elevated in individuals with a molybdenum cofactor deficiency. t. cyanide transsulfurase SYN: t. sulfurtransferase. t. sulfurtransferase a transferase that catalyzes the formation of thiocyanate … Medical dictionary
TST (gene) — Thiosulfate sulfurtransferase (rhodanese), also known as TST, is a human gene.cite web | title = Entrez Gene: TST thiosulfate sulfurtransferase (rhodanese)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView… … Wikipedia
List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… … Wikipedia
rhodanese — SYN: thiosulfate sulfurtransferase. * * * rho·da·nese rōd ə .nēz, .nēs n a crystallizable enzyme that catalyzes the conversion of cyanide and thiosulfate to thiocyanate and sulfite and that occurs in animal tissues and bacteria … Medical dictionary
cyanide poisoning — poisoning by cyanide compounds, potent rapid acting substances that cause cellular hypoxia by formation of an inactive complex of cytochrome oxidase and cyanide. Characteristics include nausea without vomiting, dizziness, convulsions,… … Medical dictionary
Cyanide poisoning — Classification and external resources Cyanide ion ICD 10 T … Wikipedia
MPST — Mercaptopyruvate sulfurtransferase, also known as MPST, is a human gene.cite web | title = Entrez Gene: MPST mercaptopyruvate sulfurtransferase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=4357|… … Wikipedia