Poly ICLC

Poly ICLC

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ATC_prefix = L03
ATC_suffix = AX08
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Poly ICLC is an immunostimulant.

It consists of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA. [cite web |url=http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=39559 |title=Definition of poly ICLC - National Cancer Institute Drug Dictionary |accessdate=2007-11-13 |format= |work=]

It is a ligand for toll like receptor-3.cite journal |author=Zhu X, Nishimura F, Sasaki K, "et al" |title=Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models |journal=Journal of translational medicine |volume=5 |issue= |pages=10 |year=2007 |pmid=17295916 |doi=10.1186/1479-5876-5-10]

References

http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=39559


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