Methylitaconate Delta-isomerase

methylitaconate delta-isomerase
Identifiers
EC number	5.3.3.6
CAS number	9059-08-9
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a methylitaconate Delta-isomerase (EC 5.3.3.6) is an enzyme that catalyzes the chemical reaction

methylitaconate $\rightleftharpoons$ 2,3-dimethylmaleate

Hence, this enzyme has one substrate, methylitaconate, and one product, 2,3-dimethylmaleate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is methylitaconate Delta2-Delta3-isomerase. This enzyme is also called methylitaconate isomerase. This enzyme participates in c5-branched dibasic acid metabolism.

References

• Kung HF, Stadtman TC (1971). "Nicotinic acid metabolism. VI. Purification and properties of alpha-methyleneglutarate mutase (B 12-dependent) and methylitaconate isomerase". J. Biol. Chem. 246 (10): 3378–88. PMID 5574401.