Glucuronate isomerase

In enzymology, a glucuronate isomerase (EC number|5.3.1.12) is an enzyme that catalyzes the chemical reaction

:D-glucuronate $ightleftharpoons$ D-fructuronate

Hence, this enzyme has one substrate, D-glucuronate, and one product, D-fructuronate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-glucuronate aldose-ketose-isomerase. Other names in common use include uronic isomerase, uronate isomerase, D-glucuronate isomerase, uronic acid isomerase, and D-glucuronate ketol-isomerase. This enzyme participates in pentose and glucuronate interconversions.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1J5S and PDB link|2Q01.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9023-87-4."

Gene Ontology (GO) codes