Cycloeucalenol cycloisomerase

Cycloeucalenol cycloisomerase
cycloeucalenol cycloisomerase
Identifiers
EC number 5.5.1.9
CAS number 60496-19-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a cycloeucalenol cycloisomerase (EC 5.5.1.9) is an enzyme that catalyzes the chemical reaction

cycloeucalenol \rightleftharpoons obtusifoliol

Hence, this enzyme has one substrate, cycloeucalenol, and one product, obtusifoliol.

This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is cycloeucalenol lyase (cyclopropane-decyclizing). This enzyme is also called cycloeucalenol---obtusifoliol isomerase. This enzyme participates in biosynthesis of steroids.

References

  • Heintz R, Benveniste P (1974). "Plant sterol metabolism. Enzymatic cleavage of the 9beta, 19beta-cyclopropane ring of cyclopropyl sterols in bramble tissue cultures". J. Biol. Chem. 249 (13): 4267–74. PMID 4369016. 
  • Rahier A, Schmitt P and Benveniste P (1982). "7-oxo-24ξ(28)-dihydrocycloeucalenol, a potent inhibitor of plant sterol biosynthesis". Phytochemistry 21 (8): 1969–1974. doi:10.1016/0031-9422(82)83024-0. 
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